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Femara is better known as letrozole.
Letrozole and clomid have similar effect, although they work differently.
Estradiol works in a negative feedback system to suppress FSH production.
Clomid blocks the estradiol receptor, making estradiol less effective at suppressing FSH production. Therefore there is more FSH production, and more follicular stimulation.
Letrozole blocks the production of estradiol. So there is less estradiol to suppress FSH production. Therefore more FSH is produced, and more follicular stimulation.
Both are oral and relatively inexpensive. They are about equally effective.
Letrozole is not FDA-approved for this use, in fact the manufacturer advises against it, but it's used this way frequently. A similar drug in the same family is anastrazole.
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