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Michelle,
Everything that I know about the two chromosomal defects is from women on the internet who have lost children from them. It is your friend's choice as to whether she wants to know for sure if her child will be born with either of these and the only way to be 100% sure is by amnio. There are risks but there are unfortunately going to be risks if the baby has these anyway. It is a tough decision and my heart goes out to her. The only thing I can add, because I've lost a baby of my own, is that it is the hardest thing a mother can go through. It is life changing and you are effected by their short life in so many ways. My prayers are that the DR is wrong with the diagnosis. My best to you both.
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