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I took letrozole ( femera ) for a few months and was also concerned with the birth defects I had read about. The RE stated the life of letrozole is short lived, you take it early enough in your cycle that by the time of conception it is out of your system.
I had no luck with the drug, but while on it, I felt ok. No bad side effects. I did ovulate once while on it versus clomid - I never did.
Good Luck !!!
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