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  #1 (permalink)  
Old 03-04-2009, 05:31 PM
wishing's Avatar
wishing wishing is offline
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Posts: 1,192
Lovenox-will it make a difference?

I have MTHFR, and I used Lovenox for IVF #2 (old RE) and IVF #3 (current RE). My current RE doesn't think it makes a difference, but he willingly let me use it for my last IVF.
I'm contemplating asking him about using it for my DE cycle since it wasn't included in my meds. I want to do everything I need to in order to get pg.
But if he hasn't told me that I need it, I'm not sure if it really is all that important.

What do you ladies think? Should I inquire about it? I'm sure he'll say it's ok, but I don't know if I should bother. (I still have tons of it at home anyway!)

I'd appreciate any input! Thanks
__________________
Me-32-MTHFR, bad egg quality
DH-32- perfect!
TTC since 2/06
4 IUIs-all BFNs


IVF #1 (Feb. 2008)
2/21-ER- 8 eggs (5 fertilized/3 not mature)

2/24 ET- 3 perfect 8-cell embies
3/10-BETA - BFN

IVF #2 (June 2008)
6/15 ER- 9 eggs retrieved/3 mature/2 fertilized

6/20 ET- 1 blast
6/30 Beta-BFN

IVF #3 (September 2008)
9/25- ER- 9 eggs (3 mature/3 fertilized)
9/28- ET- 3 embies
10/10-BFN


IVF #4 w/DE
3/19-ER- 15 eggs (12 mature/12 fertilized)
3/24-ET- 2 blasts (both 4AA) and 8 frosties
4/3- Beta #1 751 (10dp5dt)
4/6- Beta #2 3088 (13dp5dt)
4/13- Beta #3 32,321 and u/s-TWINS!
7/8- Lost twin boys at 18 weeks due to IC and PTL. Our angels are watching over us.
FET #1
9/30- Hysteroscopy #2/D&C to remove leftover tissue
11/6- Start BCPs
11/15-Start Lupron
FET- December 15th
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  #2 (permalink)  
Old 03-04-2009, 06:40 PM
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jak40 jak40 is offline
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Wishing - my (previous RE) had me use Lovenox along with low dose aspirin for IVF #1 and FET #1 (my eggs). BFN

I have a new RE, not sure if he will have me use Lovenox with DE or not.
__________________
Me (42)-tubal ligation done in '94
DH (36) -fine
DD-21 DS-18 DS-14
4/08 - IVF#1 (2) 3day 8-cell embryos
6/08 - FET#1 (3) 3day 8-cell embryos
6/09 - DE/IVF - (2) 3day 7-cell embryos
11/09 - New fertility clinic-chose donor
ER/ET in early to mid Jan '10
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Old 03-04-2009, 07:37 PM
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jencat215 jencat215 is offline
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I have the MTHFR mutation and took baby aspirin throughout my pregnancy and heparin injections for this first trimester. I had 2 previous m/c's. I totally believe that this treatment helped me carry my baby to term (and 2 days past term!). No, it doesn't help you get pregnant, but it helps you keep the pregnancy. MTHFR mutations can have issues with blood clots in the placenta and baby aspirin and heparin helps prevent that.
__________________

Me: 36 MTHFR hetero, RPL
DH: 34 Perfect
Etienne , Jake , Sam (cats) Maggie (iguana)
TTC #1: 2 yrs
2 m/c (Aug '06 and Jan '07), 1 ectopic pg (lost left tube)

5 IUI's

5/27: beta #1: 716!!!! (17dpo) Natural cycle!
5/29: beta #2: 1885!!!!
6/1: early u/s-1 sac/yolk
6/9: u/s#2-saw and heard hb! 114 bpm. Measuring 6w2d
6/17: u/s #3- hb 154 bpm. Measuring 7w3d
7/1: u/s #4- hb 161 bpm. Measuring 9w4d
7/9: first OB appt.-u/s #5- hb 152 bpm. Measuring 10w4d
7/17-NT scan-everything looks great! Measuring 11w6d
8/14-quad screen (quick gender check):
IT'S A BOY!!!

2/2/09: c-section scheduled!




check out my website! www.glassphusions.wordpress.com
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  #4 (permalink)  
Old 03-04-2009, 07:53 PM
LGB LGB is offline
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Wishing-I've done some research on this bc I had a different blood clotting test come back slightly elevated.

From what I've read, just like with other treatments/medicines for IVF, some REs use Lovenox or Heparin and some don't.

Those who do, seem to use it in patients with previous m/c's caused by a blood clot.

Those who don't, seem to use baby aspirin and Folgard (you can get the equivilant OTC by taking folic acid, vitamin B6 and vitamin B12).

I would definitely ask your RE, or check with a hematologist, if you want a 2nd opinion.

I have heard that Lovenox and Heparin can have the opposite effect so you need to be careful. My OB and REs were completely against it for me and said all I need is baby aspirin. I decided to add in Folgard bc it can't hurt.

You could also post this on the SIRM website, I did and got responses from the REs right away.
__________________
Me: 32, Stage 2 Endo, Hereditary Egg Quality Problem & Family History of IF all around!
DH: 37, Perfect-thank goodness one of us is!
TTC #1 for 2 years-6 months on our own, 3 months Letrozole with OB-BFN, 2 IUIs with Letrozole-BFN, 2 IVFs with my own eggs-BFN, DE IVF Fresh Cycle-BO m/c

FET August 31-2 4AA blasts
Beta #1 14dpo 196, Beta #2 16dpo 470, Beta #3 23 dpo 7,019
1st US at 6w1d bc of bleed (SCH found, less than 1 cm)-singleton measuring 5w6d HB 120bpm
2nd US at 7w1d-SCH 1cm-baby meausuring 6w6d HB 151bpm
3rd US at 7w5d-SCH still 1cm-baby measuring 7w5d HB 169
4th US 9w1d-SCH going away, baby measuring 9w1d HB 182
Released to OB! Stopped all meds, woo-hoo!
5th US 10w1d-SCH GONE! Baby measuring ahead at 10w3d HB 167
1st OB appt. 10//29-baby a busy bee! 11w
2nd OB appt. 11/5-baby having a party in there! 12w
3rd OB appt 12/1 16w appt.
E.D.D. May 19th, 2010!!



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  #5 (permalink)  
Old 03-04-2009, 09:40 PM
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DeannaRN DeannaRN is offline
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Posts: 641
Wishing,
I was so glad to see you post this question since I had the same question myself. I have MTHFR (compound hetero) and my RE had me use Lovenox for 1st IVF along with Folgard and baby aspirin. My 2nd IVF is going to be DE and I'm going overseas for it so will be monitored here only by an OB/GYN. I too have leftover Lovenox from my first cycle and am trying to figure out whether I should use it or not. I'm interested in hearing what others have to say.
__________________

38, DOR, MTHFR on Lovenox(compound hetero), carrier of Fragile X.
DH- 42, spinal cord injury, TESE found 0 sperm
DS- 16 from prior marriage
6 IUI's

IVF #1 10/08 chemical preg
IVF #2 5/09 DE/DS in Czech Republic chemical preg
IVF #3 8/09 Going back to Czech Republic We're not giving up yet
8/13 ER
8/18 ET 3 grade 1 blasts
8/25 + HPT
8/27 (9dp5dt) beta 252
8/31 (13dp5dt) beta 1856
9/4 (17dp5dt) beta 8984
9/14 u/s 2 sacs and 2 heartbeats. Baby A measuring 6w2d. Baby B measures 6w5d. TWINS!!
9/28 Both babies lookin good with strong heartbeats.
10/23 NT scan

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  #6 (permalink)  
Old 03-28-2009, 02:42 PM
lewlou's Avatar
lewlou lewlou is offline
lewlou
 
Join Date: Feb 2009
Posts: 70
lovenox and donor eggs

I am starting injections of lupron in a few days for donor egg cycle, I will start lovenox injections on the day of the transfer and for 30 days after that, if I am pregnant. I would'nt do this unless my doctor said to. I had a failed cycle and a my clotting was not checked until I requested it. So, it has been a learning process for me. My advice is ask a lot of questions and do not be afraid to be annoying, you must advocate for yourself and your baby to be.
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