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Journal Article http://www.springerlink.com/images/print.gif Purpose: A large part of infertility treatment involves the use of exogenous gonadotropins. The last decade has seen a progressive switch from human menopausal gonadotropin (hMG), the original gonadotropin product, to progressively more costly products, primarily or exclusively containing follicle-stimulating hormone (FSH). Though obviously at least in part driven by marketing efforts of pharmaceutical companies, this switch has received relatively little scrutiny despite its obvious cost implications. We therefore investigated whether a switch back to a generic or less costly hMG-driven ovulation induction protocol would affect patient outcome after ovulation induction and, by implications, with other assisted reproductive technologies. Methods: We prospectively studied clinical pregnancy rates in a large number of consecutive ovulation induction cycles in a well-defined patient population (group 1) which, after October of 1997, had been switched from a predominantly FSH to an hMG-driven protocol, based on an institutional formulary change. Until a transition period (between July and September 1997), this patient population had been on a primarily FSH-driven protocol (between July 1996 and June 1997). In parallel, we evaluated a second patient population (group 2), which was managed by the same physicians outside of formulary requirements and remained almost exclusively on principally FSH-driven ovulation induction cycles. Results: FSH- and hMG-driven ovulation induction protocols did not differ in pregnancy outcome during the prospective study period. Group 1 patients, however, demonstrated a significant increase in pregnancy rates after the switch from FSH to hMG stimulation had taken place (P = 0.02), while group 2 patients demonstrated no change in pregnancy rate during the same time period. Conclusions: Generic hMG products do not adversely affect pregnancy rates in comparison to more costly FSH products in routine ovulation induction cycles and should be considered an appropriate alternative to more expensive FSH products. follicle stimulating hormone (FSH) - ovulation induction - human menopausal gonadotropin Last edited by fitafita : 01-15-2008 at 05:58 PM. |
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I've used generic clomid and hcg, although they were for IUI. I would also use generic drugs for IVF. I am all for generics...save tons of money and they are just as good as the name brand stuff.
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![]() Me: 36 MTHFR hetero, RPL DH: 34 Perfect Etienne , Jake , Sam (cats) Maggie (iguana)TTC #1: 2 yrs 2 m/c (Aug '06 and Jan '07), 1 ectopic pg (lost left tube) 5 IUI's 5/27: beta #1: 716!!!! (17dpo) Natural cycle!5/29: beta #2: 1885!!!! 6/1: early u/s-1 sac/yolk 6/9: u/s#2-saw and heard hb! 114 bpm. Measuring 6w2d 6/17: u/s #3- hb 154 bpm. Measuring 7w3d 7/1: u/s #4- hb 161 bpm. Measuring 9w4d 7/9: first OB appt.-u/s #5- hb 152 bpm. Measuring 10w4d 7/17-NT scan-everything looks great! Measuring 11w6d 8/14-quad screen (quick gender check): IT'S A BOY!!! 2/2/09: c-section scheduled! ![]() check out my website! www.glassphusions.wordpress.com |
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your welcome... and you mean your first AND last IVF because this is gonna work for you!!!
Positive thoughts! ![]()
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![]() Me: 36 MTHFR hetero, RPL DH: 34 Perfect Etienne , Jake , Sam (cats) Maggie (iguana)TTC #1: 2 yrs 2 m/c (Aug '06 and Jan '07), 1 ectopic pg (lost left tube) 5 IUI's 5/27: beta #1: 716!!!! (17dpo) Natural cycle!5/29: beta #2: 1885!!!! 6/1: early u/s-1 sac/yolk 6/9: u/s#2-saw and heard hb! 114 bpm. Measuring 6w2d 6/17: u/s #3- hb 154 bpm. Measuring 7w3d 7/1: u/s #4- hb 161 bpm. Measuring 9w4d 7/9: first OB appt.-u/s #5- hb 152 bpm. Measuring 10w4d 7/17-NT scan-everything looks great! Measuring 11w6d 8/14-quad screen (quick gender check): IT'S A BOY!!! 2/2/09: c-section scheduled! ![]() check out my website! www.glassphusions.wordpress.com |
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EXACTLY, first and last! I have only found a generic form for one medication, at ivfmeds.com, it is repronex- no luck with any others. But at least that will offer some savings.
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I have used Clomiphene (Clomid generic) and Repronex for the past 2 cycles. The Repronex is still rather expensive, but not nearly as much of some of the other ones. I use IVPcare and the Repronex is aboout $120 for 2 vials. Good luck to you!
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Sheila Me - 38 - no known issues except age DH - 36 - low normal count TTC since July 2006 5/07 - normal HSG 6/17/08 - FSH 7.6 6 IUI's - all neg (one unmedicated, 3 with Clomid, 2 with Repronex) IVF #1 ![]() IVF#2 - Estrogen Priming Protocol 3/25 - ER - 7 eggs, 6 fertilized 3/28 - ET - three 8 cells - two A's and one B; froze 4 BB and 5 BC 4/4 - positive HPT 7dp3dt 4/8 - 14 dpER Beta 435; 16dpER Beta 12614/28 - u/s TWINS 7/21/09 - Two Girls!! Make a pregnancy ticker
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I used generic Lupron and it worked just fine.
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Me 32 - All tests seem fine DH 31 - Very Low Everything 2 furbabies TTC since June 2007March '08 to Aug '08 - Five IUI's, all IVF #1 Oct '08 w/ ICSI 9 eggs retrieved & 7 fertilized w/ ICSI 5 day transfer of 2 blasts, none to freeze IVF #2 Jan '09 w/ ICSI & AH 9 eggs retrieved & 7 fertilized w/ ICSI 3 day transfer of two 8-cell embryos, none to freeze ![]() IVF #3 April '09 w/ ICSI 19 Eggs Retrieved & 10 Fertilized w/ ICSI April 18 - 3 day transfer of two 8-cell embryos, none to freeze May 1 - Beta 13dp3dt 480!!!! May 5 - 1st u/s at 4 weeks, 6 days - 2 sacs ![]() May 27 - 3rd u/s at 8 wks, 2 strong heartbeats!! Aug 6 - u/s @ 18 weeks - Two GIRLS, each weighing 1/2 lb each!! Sept 22 - u/s @ 24 weeks - Girls doing great, both weighing just over 1 1/2 lbs each Oct 21 - u/s @ 28 weeks - baby A just shy of 3 lbs and baby B just over 3 lbs |
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I was a pharmacy tech for 5 years and I can tell you that by law generics and brand name drugs have to have the exact same active ingredients both in name and quantity. The only difference allowed is the name and the "filler" stuff like dyes.
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