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  #1 (permalink)  
Old 08-12-2008, 12:59 PM
TeamH's Avatar
TeamH TeamH is offline
Senior Member
 
Join Date: Jul 2008
Posts: 180
Angry Only One Follie and I Am On More Clomid

This is my third month of Clomid. The first month on 50 mg., no ovulation. Second month, 100 mg. and I ovulated two eggs. This month my RE increased my dose to 150 mg. and I only had one measurable follie of 11 mm on CD10. I thought that increasing your dose of Clomid usually causes more follies to grow, not less.

Has anyone else had this problem? Could the follies be maturing slower this time? Any insight would be much appreciated.

I am feeling frustrated and a little defeated, even though I know I have to stay positive.
__________________
Me: 35 - PCOS
DH: 39 - slightly low morphology
married 8 years

2 adorable Pugs - Huey and Yoshi

No ovulation since 12/24/07.

2/14/2008 - HSG is clear. Dr. still concerned b/c of two prior abdominal surgeries.

May 2008 - Started Clomid 50 mg. - no ovulation

June 2008 - Saw RE and started Metformin 2000 mg.
______________________
1st IUI
July 2008 - Clomid 100 mg
O'd definitely 1 and maybe 2 follies, but no pregnancy.

2nd IUI
August 2008 - Clomid 150 mg./Follitism 75 mg.
No pregnancy

3rd IUI - Three's a Charm
Sept. 3 - CD1
Sept. 5 - Start Follitism 75 mg.
Sept. 17 - IUI - 1 ripe follie, 50 mil sperm/75% mot.
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  #2 (permalink)  
Old 08-12-2008, 01:36 PM
Krista's Avatar
Krista Krista is offline
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Join Date: Nov 2007
Posts: 749
Hi Team H- Sorry to hear you're not having much luck. Maybe you just don't react well to the clomid. I know there are other oral meds out there and maybe you can try injectibles? What did your RE say about everything?
__________________
Me: 36 DH: 39
TTC since 1/07

10/07-1/08: Clomid
2/08-4/08: Found RE, testing etc
5/08-8/08: 3 IUIs- All

IVF #1: Nov '08
9/5- start BCPs
10/2- 2 large cysts found- Cycle canceled for the month
10/27 Cyst gone!
11/9- ER- 9 retrieved-4 fertilized - they "forgot" to ICSI?!
11/12- 3 day transfer of 2 Embabies- 7 & 8 cell both w/ less than 5% fragmentation
11/24- BETA

Taking a break. Don't know what we'll do next....

2 furbabies:
Tia Grommit
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  #3 (permalink)  
Old 08-12-2008, 01:57 PM
TeamH's Avatar
TeamH TeamH is offline
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Join Date: Jul 2008
Posts: 180
I have to go back in on Thursday for an ultrasound to see how things are progressing. My lining is thin too, so he increased my Estrace from two tablets per day to two tablets orally and two tablets vaginally. Fun, fun, fun.

We have not discussed injectibles yet b/c I responded last time to the Clomid. I really am not sure what the next step will be b/c he only recommended three IUIs before we move on to IVF. If this cycle does not work out, then next month would probably be our last IUI unless he has another suggestion.

Obviously I would rather not go to the IVF route b/c of the expense - my insurance does not cover.
__________________
Me: 35 - PCOS
DH: 39 - slightly low morphology
married 8 years

2 adorable Pugs - Huey and Yoshi

No ovulation since 12/24/07.

2/14/2008 - HSG is clear. Dr. still concerned b/c of two prior abdominal surgeries.

May 2008 - Started Clomid 50 mg. - no ovulation

June 2008 - Saw RE and started Metformin 2000 mg.
______________________
1st IUI
July 2008 - Clomid 100 mg
O'd definitely 1 and maybe 2 follies, but no pregnancy.

2nd IUI
August 2008 - Clomid 150 mg./Follitism 75 mg.
No pregnancy

3rd IUI - Three's a Charm
Sept. 3 - CD1
Sept. 5 - Start Follitism 75 mg.
Sept. 17 - IUI - 1 ripe follie, 50 mil sperm/75% mot.
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  #4 (permalink)  
Old 08-12-2008, 03:19 PM
AmyK's Avatar
AmyK AmyK is offline
Senior Member
 
Join Date: Aug 2007
Posts: 1,660
I had the same thing happen to me. The first month I had two follies but after that, only one. I had smaller ones, but I would always get one dominant follie that would take over.

I just moved onto Gonal-f and can say I am much happier. It is a big expense but none of the problems. My lining was great and I had 4 follies (with a few smaller ones).

Just an idea if you need it next month. In the meantime do not give up on this cycle yet. I know it is hard when you want more than one follie. You need to not think of it as JUST one and start thinking it as THE one!! If you go through the BFPs stats on the sticky at the top of this board, there are plenty of BFPs from 1 follie.

Good luck at your next scan!
__________________
~ Amy

TTC 6+ years
me - 36 (elevated FsH)
dh - 48 (perfect guy..not so perfect swimmers )
- Molly

3 unmedicated IUIs (2007) ...............BFN
1 IUI w/ Clomid/Trigger (2007) ..........BFN
HSG - All Clear!
2 IUIs w/Clomid/trigger (2008)...........BFN
05/09/08 Lap/myomectomy
08/2008 IUI #7 (gonal-f 150iu/day)....BFN
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  #5 (permalink)  
Old 08-12-2008, 04:34 PM
TeamH's Avatar
TeamH TeamH is offline
Senior Member
 
Join Date: Jul 2008
Posts: 180
Thanks Amy. I just have to get through this cycle, see how it goes and then find out from my RE what we plan to do next month.

How much do the injectibles cost?
__________________
Me: 35 - PCOS
DH: 39 - slightly low morphology
married 8 years

2 adorable Pugs - Huey and Yoshi

No ovulation since 12/24/07.

2/14/2008 - HSG is clear. Dr. still concerned b/c of two prior abdominal surgeries.

May 2008 - Started Clomid 50 mg. - no ovulation

June 2008 - Saw RE and started Metformin 2000 mg.
______________________
1st IUI
July 2008 - Clomid 100 mg
O'd definitely 1 and maybe 2 follies, but no pregnancy.

2nd IUI
August 2008 - Clomid 150 mg./Follitism 75 mg.
No pregnancy

3rd IUI - Three's a Charm
Sept. 3 - CD1
Sept. 5 - Start Follitism 75 mg.
Sept. 17 - IUI - 1 ripe follie, 50 mil sperm/75% mot.
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  #6 (permalink)  
Old 08-12-2008, 04:43 PM
AmyK's Avatar
AmyK AmyK is offline
Senior Member
 
Join Date: Aug 2007
Posts: 1,660
I used 900iu total (and alot of prayer that I wouldn't need to order more!) and I think it was around $725. A big step up from the clomid, but none of the clomid side effects. Wish I would have tried it earlier.

I will still pray that you won't need to worry about it!
__________________
~ Amy

TTC 6+ years
me - 36 (elevated FsH)
dh - 48 (perfect guy..not so perfect swimmers )
- Molly

3 unmedicated IUIs (2007) ...............BFN
1 IUI w/ Clomid/Trigger (2007) ..........BFN
HSG - All Clear!
2 IUIs w/Clomid/trigger (2008)...........BFN
05/09/08 Lap/myomectomy
08/2008 IUI #7 (gonal-f 150iu/day)....BFN
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  #7 (permalink)  
Old 08-12-2008, 05:04 PM
TeamH's Avatar
TeamH TeamH is offline
Senior Member
 
Join Date: Jul 2008
Posts: 180
I guess it is still cheaper than IVF.

Good luck in your 2ww. I went crazy last month trying to read into all my symptoms.

If the one follie grows , then my IUI should probably be Saturday and Sunday.

Thanks for the prayers. I'm sending one right back at you.
__________________
Me: 35 - PCOS
DH: 39 - slightly low morphology
married 8 years

2 adorable Pugs - Huey and Yoshi

No ovulation since 12/24/07.

2/14/2008 - HSG is clear. Dr. still concerned b/c of two prior abdominal surgeries.

May 2008 - Started Clomid 50 mg. - no ovulation

June 2008 - Saw RE and started Metformin 2000 mg.
______________________
1st IUI
July 2008 - Clomid 100 mg
O'd definitely 1 and maybe 2 follies, but no pregnancy.

2nd IUI
August 2008 - Clomid 150 mg./Follitism 75 mg.
No pregnancy

3rd IUI - Three's a Charm
Sept. 3 - CD1
Sept. 5 - Start Follitism 75 mg.
Sept. 17 - IUI - 1 ripe follie, 50 mil sperm/75% mot.
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  #8 (permalink)  
Old 08-15-2008, 06:33 AM
MiMa12's Avatar
MiMa12 MiMa12 is offline
TTC Miracle #1 =)
 
Join Date: Apr 2008
Posts: 154
hey girl!!! just wanted to see how things were with u. how r u feeling?? hope evrything is going good!!!!


__________________

MiMa MaRk
Karina (25) - so far so good
dh (24) - low everything [ugh]
TTC #1 - 6 long yrs
-------
'07 HSG - excellent!
IUI #1
4/8 - u/s everything looked good
4/10-14 - started 1st round of clomid 50 mgs (CD3-7)
4/18 - start opk (CD11)
4/20 - bw & us 3 follies (CD13)
4/21 - u/s and trigger shot woohoo!
4/22 - IUI at 9am.. start progesterone suppository
5/6 - beta BFN

IUI #2
7/5 - AF showed! couldnt be happier!!
7/7 - u/s start clomid (CD 3)
7/17 - u/s 2 follies (CD 14)
7/19 - iui bad numbers 200k & 30%
8/1 - POAS - BFN
*back to RE in Nov woot!!*



for my lil miracle baby


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  #9 (permalink)  
Old 08-15-2008, 02:16 PM
elaine123 elaine123 is offline
Senior Member
 
Join Date: May 2008
Posts: 184
That happened to me...just look at my signature. I remember hearing somewhere that clomid is not good to be on for too long b/c it starts not to work and starts to have a negative impact on the lining of your uterus.
__________________
Me 31 - All tests seem fine, dx Hashimotos
DH 30 - Low Sperm Count, Morphology & Motility
2 furbabies
TTC since June 2007

March '08 - First IUI, on clomid,
April '08 - Second IUI, on clomid,
May '08 - Third IUI, on clomid & metformin,
July '08 - Fourth IUI, on clomid & metformin,
Aug '08 - Fifth & Final IUI, on Femara,

IVF #1 October '08
9 eggs retrieved & 7 fertilized w/ ICSI
Transferred 2 blasts, none to freeze



IVF #2 in Jan '09
11/15/08 - Start BCP's, Baby Asprin, Royal Jelly
11/18/08 - Meet w/ RE to discuss Jan cycle
12/15/08 - Scheduled to start Lupron
ER tentatively scheduled for week of Jan. 5th!
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  #10 (permalink)  
Old 08-15-2008, 03:12 PM
TeamH's Avatar
TeamH TeamH is offline
Senior Member
 
Join Date: Jul 2008
Posts: 180
Quote:
Originally Posted by MiMa12
hey girl!!! just wanted to see how things were with u. how r u feeling?? hope evrything is going good!!!!



Hi Mima! I was wondering how you were doing too. When is your RE appt.?

I am doing so so. This cycle has been challenging. Not only did the increase in Clomid cause me to be sick (threw up and was nauseated the entire time I took it) my body did not respond well to it. I had my CD13 u/s yesterday and there are follies, but they are small. So my doctor started me on Follitism 75 mg. once a day and I am supposed to go back on Sunday for an u/s and b/w to check hormones and follies. I really pray that this will get me to ovulate. I would hate to miss a cycle. I think when you don't have to deal with IF issues, a month goes by fast. When you are, it seems to move a snails pace.

Elaine-
This is only my third month on Clomid, so I am surprised that it is not working as well, especially since I responded well last month. My lining was a little thin but my doctor doubled my dose of Estrace and it is now looking pretty good. It was 8+ mm. on my last u/s.
__________________
Me: 35 - PCOS
DH: 39 - slightly low morphology
married 8 years

2 adorable Pugs - Huey and Yoshi

No ovulation since 12/24/07.

2/14/2008 - HSG is clear. Dr. still concerned b/c of two prior abdominal surgeries.

May 2008 - Started Clomid 50 mg. - no ovulation

June 2008 - Saw RE and started Metformin 2000 mg.
______________________
1st IUI
July 2008 - Clomid 100 mg
O'd definitely 1 and maybe 2 follies, but no pregnancy.

2nd IUI
August 2008 - Clomid 150 mg./Follitism 75 mg.
No pregnancy

3rd IUI - Three's a Charm
Sept. 3 - CD1
Sept. 5 - Start Follitism 75 mg.
Sept. 17 - IUI - 1 ripe follie, 50 mil sperm/75% mot.
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