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Angie: I know what you mean about the genetic defects being passed on if it is a male child. I know that there is a procedure (I forget the acronym but maybe pgd??) where they can determine the sex of the embryo and if there are any major genetic issues before even implanting it. This is probably really expensive and I imagine there are some risks involved to the embryo. The benefit would be to determine if the embryo was a girl you wouldn't have to worry about passing on the genetic defects.
It is pretty daunting to think that very soon there could be some surgery for your DH. My DH may be put on the hCG as well if the Clomid doesn't work.
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Chris Me: 35 10/09: Fertility labwork cycle day 2 and 21 FSH Normal at 7.2 DH: 33 Azoospermia, unknown cause FSH 39! LH 11.9 T level ~150 ( Was placed on Androgel but he stopped that when we realized it is contraindicated for sperm production ) 10/08/09: 1st phone consult with Dr Turek 10/13/09: 1st official appt. with Dr. Turek ![]() Start Clomid to raise T levels 11/10/09: Testosterone 428! Clomid is working. 11/09: Genetic tests/chromosomal analysis. Normal male karyotype. Australian Shephard Arya and Big Fat Cat Kahless
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Angie--I read your post about genetic defects being passed on to children. My DH was recently diagnosed with a y-chromosome microdeletion (in the AZFc region). This means that if we are lucky enough to do the mTESE and have sperm found, and have a successful IVF/ICSI and had a baby boy, he would definitely have the same deletion. (Daughters will not be affected). As sad as it is to think about (having a child go through the same thing we are going through) I would not think twice about moving forward. My DH is the most wonderful, loving, caring person--and if his mother had been able to look into the future while she was pregnant with him and see the type of person he would grow up to be--and know he'd have to go through the infertility aspect--I can't imagine her ever having second thoughts either. Know what I mean? My DH is perfectly happy and healthy and normal--it's just the pesky microdeletion that affects nothing but fertility.
If we had a son, I feel like science will have such breakthroughs in the next 20 or so years, that by the time he is thinking of having children, it will be much easier than it is for us today. When Dr. Schlegel told me about the defect being passed on to any sons, I barely even flinched. It just isn't something that would ever stop me from moving forward. It won't stop him from leading a normal and healthy life--it will just be a bump in the road like it is for us. I can't imagine not having my DH--so as sad as I am that we have to go through this, I am just thankful to have him in the first place. sorry...feeling extra emotional and sappy tonight because DH left for Ohio on a 10 day hunting trip this morning! It's sad coming home to an empty house! hope everyone is doing well! erin
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Me: 25, no known problems Husband: 27, Azoospermia Together since 3/22/2002, Married since 6/16/2007 So Far: 11/08: Began TTC 6/5/09: 1st SA: Zero Sperm 6/22/09: 2nd SA--Zero Sperm again.... 7/8/09: Bloodwork labs 7/29/09: Normal scrotal & prostate U/S. Normal physical exam. 8/1/09: FSH 12.3, LH 22.8, Prolactin 17.2, Testerone 952....all seem high. September 09: Small pituitary tumor found in MRI, this is not a contributing factor and not something they are concerned about. September 09: 2nd round of blood labs are drastically different and estradiol shows as elevated (not tested before) 10/6/09: Karyotype normal, but y-chromosome microdeletion is positive. "both markers for AZFc are deleted" (local urologist made it seem like we had zero chance after this diagnosis) Upcoming: 11/17: In-person consultation with Dr. Schlegel in NYC! (Initial reaction from him via email is that we have a 70% chance of successful mTESE!) |
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Erin: I feel the same way!! I agree that by the time any sons we had are our age, they will have so many more medical advances when it comes to fertility. Just think how far they have come since we were born.
Funny you mention Ohio. I am from there, born in Marietta, went to Ohio University for undergrad and Ohio State for veterinary school. I moved to California right after I graduated vet school. Hunting was huge there but not big here in San Francisco. It is this time of year I really miss fall and colder weather. I used to go to the fall pumpkin festivals and would get apple butter, now that is one thing you just don't see out here. Darn, now I am craving it. AFM: AF is super late, I am at day 35 and counting. I am sure it is the stress of the job situation. DH just got his estradiol levels tested and they are high normal so Dr. Turek wants to start Arimidex. We are trying to get Kaiser to approve it but I know it is pricey. We will pay out of pocket if necessary but we have funds set aside for IF and don't want to touch it until we absolutely have to. Could this stuff get any more complicated???
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Chris Me: 35 10/09: Fertility labwork cycle day 2 and 21 FSH Normal at 7.2 DH: 33 Azoospermia, unknown cause FSH 39! LH 11.9 T level ~150 ( Was placed on Androgel but he stopped that when we realized it is contraindicated for sperm production ) 10/08/09: 1st phone consult with Dr Turek 10/13/09: 1st official appt. with Dr. Turek ![]() Start Clomid to raise T levels 11/10/09: Testosterone 428! Clomid is working. 11/09: Genetic tests/chromosomal analysis. Normal male karyotype. Australian Shephard Arya and Big Fat Cat Kahless
Last edited by SFBaygirl : 11-04-2009 at 06:37 PM. |
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Hello Ladies.
Kris - I hear you on the insensitive comments... they never stop around me... and most of the time they are from people that know about our IF... this Friday out to be interesting... we have a company dinner and both of my boss' pregnant wives will be there... great. I'm keeping my distance! Hello all else!
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Husband - 35 - NOA/SCO Azoospermia Me - 32 - no known fertility issues, treated for endometriosis. Married - 6/2004 TTC - 5 years 9/16/09 - Surgery to remove Endo (Level 3). 8/18/o9 - Diagnosed with Endo 1/12/09 - Surgery tumor removed (benign) and biopsy - No sperm found ![]() 12/30/08 - Can't rule out cancer, must operate. 12/24/08 - MRI and BW 12/2/08 - U/S results - Mass around left testicle. ![]() ![]() ![]() 11/25/08 - News of Low test. (177), high FSH (16.9) and LH (15.6)... 11/15/08 - First UR visit. Abnormal exam. Small and soft testes, not a blockage. Doctor is confident it is testicular failure. ![]() 11/01/08 - Normal karyotype / no deletions ![]() 10/08 - S/A = no sperm again. 09/08 - S/A= no sperm 09/17/08 - First fertility doctor's visit... we were so hopeful... Coming up: Next June - mTESE/IVF/ICSI |
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Singing: I totally agree with staying on the other side of the table or dining room if necessary. They will be talking baby non-stop I am sure.
I can't believe even people who know about your IF still make dumb comments. I am just convinced that the little filter in our brains that keeps us from saying/doing stupid things is missing in about 75% of people. Seriously!! Is your DH taking the Arimidex? I thought you had mentioned that a long time ago.
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Chris Me: 35 10/09: Fertility labwork cycle day 2 and 21 FSH Normal at 7.2 DH: 33 Azoospermia, unknown cause FSH 39! LH 11.9 T level ~150 ( Was placed on Androgel but he stopped that when we realized it is contraindicated for sperm production ) 10/08/09: 1st phone consult with Dr Turek 10/13/09: 1st official appt. with Dr. Turek ![]() Start Clomid to raise T levels 11/10/09: Testosterone 428! Clomid is working. 11/09: Genetic tests/chromosomal analysis. Normal male karyotype. Australian Shephard Arya and Big Fat Cat Kahless
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Joy - Congrats on your
!!!SFGirl - Ohio is wonderful! I especially love the Athens area...dh and I go about once a year and spend a week in Hocking Hills...it is so peaceful! Hello everyone!
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me - (31) perfectly healthy dh - (31) TESE in August, found lots of sperm Duke - german shepard Greta - german shorthair pointer August 08 - IVF #1 (13 eggs, 11 mature, 9 fert, 2 transferred, 1 frozen) September 08 - FET #1 IVF # 2 10/31 start meds 11/20 ER (12 eggs, 7 mature, 4 fertilized) 11/22 ET (3 grade C embies) 12/04 Beta 231 12/08 Beta 1,236 12/12 Beta 5,45412/19 U/S, saw heartbeat and yolk sac!, 1/05 U/S , hb 174, measuring perfect, Graduated to OB 1/19 first appt with OB, hb 172 IT'S A GIRL!!! 8/21/09 AIDA MARIE ARRIVED!! |
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SF - Dr. Boyle first prescribed Arimidex but it was too expensive for us... it was like $400/month... that's a lot. Considering I got clomid for less than $30... it was a no brainer. She would have preferred Arimidex, but Clomid was her second choice.
I'm affraid it is not working... I would expect that if his T is increasing, he would have a stronger sex drive... but that hasn't changed. We'll see only tests will tell.
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Husband - 35 - NOA/SCO Azoospermia Me - 32 - no known fertility issues, treated for endometriosis. Married - 6/2004 TTC - 5 years 9/16/09 - Surgery to remove Endo (Level 3). 8/18/o9 - Diagnosed with Endo 1/12/09 - Surgery tumor removed (benign) and biopsy - No sperm found ![]() 12/30/08 - Can't rule out cancer, must operate. 12/24/08 - MRI and BW 12/2/08 - U/S results - Mass around left testicle. ![]() ![]() ![]() 11/25/08 - News of Low test. (177), high FSH (16.9) and LH (15.6)... 11/15/08 - First UR visit. Abnormal exam. Small and soft testes, not a blockage. Doctor is confident it is testicular failure. ![]() 11/01/08 - Normal karyotype / no deletions ![]() 10/08 - S/A = no sperm again. 09/08 - S/A= no sperm 09/17/08 - First fertility doctor's visit... we were so hopeful... Coming up: Next June - mTESE/IVF/ICSI |
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Singing - DH took clomid for 2 months and his highest number was 175...he never had any side effects or signs that the meds were working. His numbers did not skyrocket but they did go up! Hope the clomid works for you!
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me - (31) perfectly healthy dh - (31) TESE in August, found lots of sperm Duke - german shepard Greta - german shorthair pointer August 08 - IVF #1 (13 eggs, 11 mature, 9 fert, 2 transferred, 1 frozen) September 08 - FET #1 IVF # 2 10/31 start meds 11/20 ER (12 eggs, 7 mature, 4 fertilized) 11/22 ET (3 grade C embies) 12/04 Beta 231 12/08 Beta 1,236 12/12 Beta 5,45412/19 U/S, saw heartbeat and yolk sac!, 1/05 U/S , hb 174, measuring perfect, Graduated to OB 1/19 first appt with OB, hb 172 IT'S A GIRL!!! 8/21/09 AIDA MARIE ARRIVED!! |
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Singing: Like Amy said, the T levels aren't going to go up nearly as much as with a true supplement like Androgel. Dr. Turek is hoping for above 200. I wouldn't expect the same physical changes. As for the Arimidex, it is my understanding that it is an estrogen blocker. Dr. Turek wants my DH on that in addition to the Clomid.
Amy: I miss Athens so much. That is where I met my DH. We were both students at OU. We lived in the same dorm . We were so young not even able to legally buy a beer at the time. Do you remember what your DH's T levels were before the Clomid? Did you guys have a successful TESE after the Clomid? I hope you and Aida are doing well and staying healthy.
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Chris Me: 35 10/09: Fertility labwork cycle day 2 and 21 FSH Normal at 7.2 DH: 33 Azoospermia, unknown cause FSH 39! LH 11.9 T level ~150 ( Was placed on Androgel but he stopped that when we realized it is contraindicated for sperm production ) 10/08/09: 1st phone consult with Dr Turek 10/13/09: 1st official appt. with Dr. Turek ![]() Start Clomid to raise T levels 11/10/09: Testosterone 428! Clomid is working. 11/09: Genetic tests/chromosomal analysis. Normal male karyotype. Australian Shephard Arya and Big Fat Cat Kahless
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erin and sfbaygirl: I totally understand where you are coming from with that. We have decided if it comes down to it and we have a genetic problem that we would go directly to DS since I let him make that decision. He told me that he did not want his son ever having to go through this and maybe having trouble finding someone since he would know it would be hard to have children financially and emotionally. I would support him with either decision since I can see both sides. He could change his mind since we all know the path of infertility is one big emotional rollercoaster!
Erin: I hope you feel better! I hate when my DH is away and the house is all lonesome--then again at least one night I know I can rent all of the chick flicks I want without him complaining Like both of you, I could never imagine life without my DH and am thankful he is here! We will see what the results will say---either way there will be a baby in our lives that will be ours ![]()
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me-30 (normal) DH-31 (azoospermia) Married 6/5/2004. Together since 1998. TTC-10/2008 1st SA Aug 09-0 Low Testosterone 158, FSH 26, LH 6 2nd SA Sept 09-0 Oct 3, 2009--Visit with Dr. Vaughn at Texas Fertility Clinic. Ordered Micro Y Deletion test for DH. Nov. 9, 2009--Deletion in A, B, and C. DS the only way to have children. Taking a breather at the moment......... |
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Angiefl, Diana83, Kris, SFBayGirl, thank you all for the encouragement and best wishes, you are sweet!!!
Lostandconfused, it is strange that the straw did not survive freezing... How do they test this????? Because as far as I know, frozen sperm when defrosted (is that the word??? sorry if not) may remain immotile as well. Then how do they know whether they are alive or not? They do not show "signs of life"... They may sting one single sperm and check it somehow, but even then, how does it prove that the others did not survive???? It is very strange... If I were you, I would trust my DH's frozen sperm too. Anyway, good luck with Sunday, I will think of you.
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Atiz Wanting a baby since Oct 2007 Azoospermia diagnosed in Aug 2008 Husband's genetic tests turn out OKAY in Oct 2008 Biopsy turns out OKAY (Johnssen score: 9) in Jan 2009 First IVF with immotile frozen thaw in Apr 2009 (stimulation is total failure, only 5 eggs of which all immature - only 1 fertilized, no embryos at all for transfer) Second IVF with immotile frozen thaw in Jul 2009 (stimulation is very bad, even with the strongest shots only 4 eggs - none fertilized, no embryos at all for transfer) THIRD IVF with fresh live sperm !!!!! three 8-cell embryos transferred on 9 November - waiting for blood test
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SFBay - dh's T started at 150 and went up to 175. We did have a successful TESE.
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me - (31) perfectly healthy dh - (31) TESE in August, found lots of sperm Duke - german shepard Greta - german shorthair pointer August 08 - IVF #1 (13 eggs, 11 mature, 9 fert, 2 transferred, 1 frozen) September 08 - FET #1 IVF # 2 10/31 start meds 11/20 ER (12 eggs, 7 mature, 4 fertilized) 11/22 ET (3 grade C embies) 12/04 Beta 231 12/08 Beta 1,236 12/12 Beta 5,45412/19 U/S, saw heartbeat and yolk sac!, 1/05 U/S , hb 174, measuring perfect, Graduated to OB 1/19 first appt with OB, hb 172 IT'S A GIRL!!! 8/21/09 AIDA MARIE ARRIVED!! |
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Amy: My DH's T was about 150 also. It is good to know that he had the successful TESE even with those levels. We will be having the T levels retested in a week or so. I will be quite curious as to the response (if any) to the Clomid.
Atiz: Thanks. This weekend is the test right? . I can't wait to hear the results.Lost: coming your way too. How is your sister doing? Is she on these forums as well?Joy: How does it feel to be ? How stoked are you and your DH?Angie: It is great that you and your DH have planned for all contingencies. That will make it soooo much easier once you get results. You have already gotten through the most difficult part which the DS discussion if you ask me. For me, emotional pain is far worse than physical so I consider that decision a huge hurdle. Erin, Singing, Kris, Mille, 3rdtimes, Melc, Katie, Schatzi, Sarah, Armywife and everyone else, have a great evening and TGIF tomorrow.
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Chris Me: 35 10/09: Fertility labwork cycle day 2 and 21 FSH Normal at 7.2 DH: 33 Azoospermia, unknown cause FSH 39! LH 11.9 T level ~150 ( Was placed on Androgel but he stopped that when we realized it is contraindicated for sperm production ) 10/08/09: 1st phone consult with Dr Turek 10/13/09: 1st official appt. with Dr. Turek ![]() Start Clomid to raise T levels 11/10/09: Testosterone 428! Clomid is working. 11/09: Genetic tests/chromosomal analysis. Normal male karyotype. Australian Shephard Arya and Big Fat Cat Kahless
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Very quiet today! I hope everyone is doing well today. I go tomorrow for another follie check to see how I am progressing. I'm excited to see how things are going!
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Me-33 DH-34--SCO Married-10 yrs TTC-9.5 yrs 2 Rat Terriers-10 and 10.5 years 10 failed IUIs 10/08: IVF #1 MDL--BFN 02/09: FET #1 BFN 04/09: IVF#2 MDL--BFN 06/09: verified reaction (pimply rash) to progesterone 08/09: IVF#3 MDL-- 4w4d10-11/09: IVF #4 Luteal Lupron 10/13: Start Lupron 10/27: Baseline 10/31: Start Stims 11/12: ER 11/15: ET 11/26 (11/27): Beta |
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