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Old 09-10-2008, 09:40 AM
karystos karystos is offline
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Join Date: May 2007
Posts: 88
is there any hope?

Just had consultation with RE after 3rd failed IVF. I had a chem preg with this one. My eggs are "perfect". But my DHs sperm is poor quality.
3% morphology
Since last year his sperm has gone from 10% to 3%. His counts and everything else have plummeted. The RE said that for this IVF the embryologist had to treat it as a biopsy case because they had trouble finding any good quality sperm for my 11 eggs. I did get 100% fertilization though which I would think wouldn't happen if his quality was so poor.

The Re told us to stop taking the fertility vitamins and to make "lifestyle" changes.

Does anyone have any ideas/experiences that could help? I'm 39. My RE wants us to wait 3 months for another SA test.

I feel there is no hope to having a biological child with my DH>
__________________
me-39 IR
dh-47 male factor my soulmate
2 IUIs w/clomid
ivf#1 1/07
antral follicle count 7
follistim, menopur, gonarelex
RE 16 eggs
TX 2 : 2A/2B embies OHSS

fet #1 5/07
2 frozen blasts
both thawed but
ivf#2 8/07
antral follicle count 15
follistim, menopur, gonarelex
RE 17 eggs
TX 3 embies: 7cellB. 6cellA, 5cellA
OHSS again! and
ivf #3 5/08 converted to IUI
new RE
long lupron protocol with gonal-F, menopur
RE : CANCELLED b/c of very slow response
released 5 perfect eggs with 80,000 post wash sperm
beta: June 5th...my 3rd anniversary
ivf #4 7/08
antral follicle count 19 eggs
long lupron (.05) with gonal-f and menopur
gonal-f only 5 days, switched to 150 menopur only
ER: 7/30 12 eggs!
ET 8/2 tx day 3- 4 embies
8/18 but turned to chem preg.
RE says it's my DH's poor sperm quality.
Appt w/Dr. Schlegel at Cornell urology
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  #2 (permalink)  
Old 09-10-2008, 05:55 PM
Tree's Avatar
Tree Tree is offline
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Join Date: Feb 2008
Posts: 215
Hi karystos. What does he mean "lifestyle changes"? And why would you stop taking the fertility vitamins? May I ask what they are?

I do not have experience in this but I would suggest DH take some things for his sperm like OKG (the body turns it into arginine which is a better way to go since regular supplemental arginine is not very well absorbed). Almonds (make sure they are raw and not roasted and salted) are good for sperm as well.

Don't give up hope. There are things you can do to improve his sperm. And hey, you got 100% fert rate as it is! Good luck.
__________________
Me 39 Blocked Tubes
DH 38 Perfect
Maggie, Lab/Chow
Gigi, grey/orange calico
Lily, dark brown tabby & sister to Gigi
TTC 4 years
1st IVF 12/07 BFN
FET 3/07 BFN

2nd IVF 7/08
Lupron 7/4/08
FSH 7/14/08
ER 7/25/08 - 23 eggs/20 fert
ET 7/28/08 - 4!
None made it to freeze
BETA 8/7/08 -
Currently "in between" treatments but pursuing TCM, Yoga, getting as healthy as I can.
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  #3 (permalink)  
Old 09-10-2008, 07:08 PM
desperate desperate is offline
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Join Date: Aug 2008
Posts: 252
Well, it sounds like your RE is giving up on you. That's kind of the position I'm in right now too. My RE basically told us after 2 failed IVF's that she wasn't sure what else to recommend. I was devasted. I make lots of eggs, and for some reason our embryos aren't good quality.

I've taken our cases into my own hands. Researched top clinics and set up appointments to get second oppinions and find out what/if anything else can be done, before we just accept it, and throw in the towel.

If MF is the problem (and it is in our case too) I'm considering having an SCSA test on DH just to confirm that it is actually the sperm that is our problem. there has been debate due to varying SA tests. www.scsadiagnostics.com

there is also a process called IMSI, and PICSI that in combination with ICSI -- is used to select and sort sperm at a much higher level than most labs use. I researched them, but didn't have many luck with labs in the US using this technique yet, although there are a few I think.

Others have told me better labs, yeild better results. There is always a different protocol, testing, etc.

I wouldn't give up and just listen to your RE. I would keep taking prenatal vitamins and get yourself some consultations set up asap. After all you've been through, you owe it to yourself to know for sure before just giving up.

GOOD LUCK!!!!!! And don't lose hope before you have to. I've been happy with my consults so far and found them very encouraging and enlightening.
__________________
Lisa

Me -- 33
hypothyroidism, ASAB
DH -- 35
MF IF (low mot, 1% morph)
** Poor embies. None ever make blast.

2 yrs TTC -
6 mths Clomid -
12 IUI's -
IVF#1 - 17 retrvd, 12 mature, 7 fertilized w ICIS. Trsfed 2 good day3 embies - No frosties - none made blast.
IVF#2 - canceled due to cyst.
IVF#3 - 18 retrvd, 15 mature, 10 fertilized w ICIS. Trsfred 2 day5 morulas -- 2 morulas frozen. None made blast.
FET - Cnxld. Embryos survived thaw, arrested b4 transfer.
**Consult w SIRM & CCRM. Started adoption papers. Chose CCRM!
IVF#4 - After 12 days of lupron and not supressed, switched to Antagonist.
28 retrvd, 14 mature, 11 fertilized w ICSI. 5 more eggs became mature on day 2, and fertilized with ICSI --for a total of 16! Transfd 1 advd blast, 1 early blast (AH), 1 morula (AH).
BETA 1(9dp5dt)-151
BETA 2(11dp5dt) - 375!
BETA 3- This thursday
U/S - Dec. 15th

http://waywardstork.blogspot.com/
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  #4 (permalink)  
Old 09-10-2008, 07:14 PM
desperate desperate is offline
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Join Date: Aug 2008
Posts: 252
My DH takes fertility vitamins (FERTILAID) that you can buy on-line. He eats nuts, takes royal jelly, eats whole organic diet with lots of protein and folic acid (apparently good for men as well) and antioxidants, and gets acupuncture to help with sperm samples. He also had a varicoceletomy. And actually, something has worked because orginally our RE told us that MF was definetly our issue and lately they are saying his samples look better and aren't so sure. now we are unexplained.
__________________
Lisa

Me -- 33
hypothyroidism, ASAB
DH -- 35
MF IF (low mot, 1% morph)
** Poor embies. None ever make blast.

2 yrs TTC -
6 mths Clomid -
12 IUI's -
IVF#1 - 17 retrvd, 12 mature, 7 fertilized w ICIS. Trsfed 2 good day3 embies - No frosties - none made blast.
IVF#2 - canceled due to cyst.
IVF#3 - 18 retrvd, 15 mature, 10 fertilized w ICIS. Trsfred 2 day5 morulas -- 2 morulas frozen. None made blast.
FET - Cnxld. Embryos survived thaw, arrested b4 transfer.
**Consult w SIRM & CCRM. Started adoption papers. Chose CCRM!
IVF#4 - After 12 days of lupron and not supressed, switched to Antagonist.
28 retrvd, 14 mature, 11 fertilized w ICSI. 5 more eggs became mature on day 2, and fertilized with ICSI --for a total of 16! Transfd 1 advd blast, 1 early blast (AH), 1 morula (AH).
BETA 1(9dp5dt)-151
BETA 2(11dp5dt) - 375!
BETA 3- This thursday
U/S - Dec. 15th

http://waywardstork.blogspot.com/
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  #5 (permalink)  
Old 09-10-2008, 07:20 PM
desperate desperate is offline
Senior Member
 
Join Date: Aug 2008
Posts: 252
Plus, you can do ICIS and also use the TESE method of extracting the sperm directly from the testicle. Have you done this yet? some say it yeilds better results. We are going to ask about this.
__________________
Lisa

Me -- 33
hypothyroidism, ASAB
DH -- 35
MF IF (low mot, 1% morph)
** Poor embies. None ever make blast.

2 yrs TTC -
6 mths Clomid -
12 IUI's -
IVF#1 - 17 retrvd, 12 mature, 7 fertilized w ICIS. Trsfed 2 good day3 embies - No frosties - none made blast.
IVF#2 - canceled due to cyst.
IVF#3 - 18 retrvd, 15 mature, 10 fertilized w ICIS. Trsfred 2 day5 morulas -- 2 morulas frozen. None made blast.
FET - Cnxld. Embryos survived thaw, arrested b4 transfer.
**Consult w SIRM & CCRM. Started adoption papers. Chose CCRM!
IVF#4 - After 12 days of lupron and not supressed, switched to Antagonist.
28 retrvd, 14 mature, 11 fertilized w ICSI. 5 more eggs became mature on day 2, and fertilized with ICSI --for a total of 16! Transfd 1 advd blast, 1 early blast (AH), 1 morula (AH).
BETA 1(9dp5dt)-151
BETA 2(11dp5dt) - 375!
BETA 3- This thursday
U/S - Dec. 15th

http://waywardstork.blogspot.com/
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  #6 (permalink)  
Old 09-11-2008, 07:17 AM
karystos karystos is offline
Member
 
Join Date: May 2007
Posts: 88
He was taking Theralogix Fertility for Men and originally it helped ...the numbers went up but never to "normal". RE thinks because it's not FDA approved...there might be something in there making it worse. ....I don't believe it but we'll try it just to rule it out. Of course we have to wait 3 months for a new batch to test.

I also made an appt with Dr Schlegel at Cornell for a consultation...to see what he thinks....

I had to accept alot of things about my DH when I married him...and I have had a happy marriage....but I never thought I had to accept another thing. I want a baby so badly..my father is sick and needs to see a grandchild.
__________________
me-39 IR
dh-47 male factor my soulmate
2 IUIs w/clomid
ivf#1 1/07
antral follicle count 7
follistim, menopur, gonarelex
RE 16 eggs
TX 2 : 2A/2B embies OHSS

fet #1 5/07
2 frozen blasts
both thawed but
ivf#2 8/07
antral follicle count 15
follistim, menopur, gonarelex
RE 17 eggs
TX 3 embies: 7cellB. 6cellA, 5cellA
OHSS again! and
ivf #3 5/08 converted to IUI
new RE
long lupron protocol with gonal-F, menopur
RE : CANCELLED b/c of very slow response
released 5 perfect eggs with 80,000 post wash sperm
beta: June 5th...my 3rd anniversary
ivf #4 7/08
antral follicle count 19 eggs
long lupron (.05) with gonal-f and menopur
gonal-f only 5 days, switched to 150 menopur only
ER: 7/30 12 eggs!
ET 8/2 tx day 3- 4 embies
8/18 but turned to chem preg.
RE says it's my DH's poor sperm quality.
Appt w/Dr. Schlegel at Cornell urology
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  #7 (permalink)  
Old 09-11-2008, 01:48 PM
elaine123 elaine123 is offline
Senior Member
 
Join Date: May 2008
Posts: 186
I would switch RE's. My DH also has 3% strict morphology and my RE said that when you do IVF w/ ICSI, the male factor is completely taken out of the equation. So you end up with just as good a chance as a couple with no male factor issues. I would try IVF w/ ICSI with a new RE.
__________________
Me 31 - All tests seem fine, dx Hashimotos
DH 30 - Low Sperm Count, Morphology & Motility
2 furbabies
TTC since June 2007

March '08 - First IUI, on clomid,
April '08 - Second IUI, on clomid,
May '08 - Third IUI, on clomid & metformin,
July '08 - Fourth IUI, on clomid & metformin,
Aug '08 - Fifth & Final IUI, on Femara,

IVF #1 October '08
9 eggs retrieved & 7 fertilized w/ ICSI
Transferred 2 blasts, none to freeze



IVF #2 in Jan '09
11/15/08 - Start BCP's, Baby Asprin, Royal Jelly
11/18/08 - Meet w/ RE to discuss Jan cycle
12/15/08 - Scheduled to start Lupron
ER tentatively scheduled for week of Jan. 5th!
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  #8 (permalink)  
Old 09-11-2008, 03:35 PM
karystos karystos is offline
Member
 
Join Date: May 2007
Posts: 88
Quote:
Originally Posted by elaine123
I would switch RE's. My DH also has 3% strict morphology and my RE said that when you do IVF w/ ICSI, the male factor is completely taken out of the equation. So you end up with just as good a chance as a couple with no male factor issues. I would try IVF w/ ICSI with a new RE.

But my embryos never make it to 8 cells on day 3 because of the sperm quality. So yes, ICSI fixes the fertilization maybe but not the embryo growth. And low morphology causes frequent miscarriages...I've had 2. So you see even with ICSI, it still is a big problem.
__________________
me-39 IR
dh-47 male factor my soulmate
2 IUIs w/clomid
ivf#1 1/07
antral follicle count 7
follistim, menopur, gonarelex
RE 16 eggs
TX 2 : 2A/2B embies OHSS

fet #1 5/07
2 frozen blasts
both thawed but
ivf#2 8/07
antral follicle count 15
follistim, menopur, gonarelex
RE 17 eggs
TX 3 embies: 7cellB. 6cellA, 5cellA
OHSS again! and
ivf #3 5/08 converted to IUI
new RE
long lupron protocol with gonal-F, menopur
RE : CANCELLED b/c of very slow response
released 5 perfect eggs with 80,000 post wash sperm
beta: June 5th...my 3rd anniversary
ivf #4 7/08
antral follicle count 19 eggs
long lupron (.05) with gonal-f and menopur
gonal-f only 5 days, switched to 150 menopur only
ER: 7/30 12 eggs!
ET 8/2 tx day 3- 4 embies
8/18 but turned to chem preg.
RE says it's my DH's poor sperm quality.
Appt w/Dr. Schlegel at Cornell urology
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  #9 (permalink)  
Old 09-15-2008, 07:04 PM
Butterfly Butterfly is offline
Junior Member
 
Join Date: Jul 2008
Posts: 19
Just wanted to suggest The Infertility Cure by Dr Randine Lewis. There are dietary changes that a man can do in order to help his issue as well as vitamins that ARE FDA approved. I believe she suggests taking pycnogenol for morph issues.

((((hugs))))

All the very best to you.
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Butterfly
TTC since Nov '05

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