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  #1  
Old 05-26-2011, 07:43 PM
Lilyrose1's Avatar
Lilyrose1 Lilyrose1 is offline
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Join Date: May 2011
Posts: 219
PCOS and depakote

Hey everyone! Anyone out ther with PCOS who has taken depakote in the past? Just curious since they think there is a link, and I was on it for ten years and developed PCOS in that time period. Just wandering if anyones in the same boat. Thanks!
__________________
Married 3 years
TTC 2 years
Me 33 PCOS
DH 33 SA good
DD 12 Jaleen Rose(from previous relationship)
Lily, Marbles, Princess, and Eddie

Insurance only covers 3 cyles iui or ivf, so...
ivf#1
8/7/11 Transferred 1 perfect blast-
9/21/11 Loss of HB at 9 weeks - Devastated
2 snowbabies

Feb. FET
2/28- ET- 2 blastocysts
3/23- US 2 lil' peanuts & 2 lil' h/b's!
4/2- SCH with bleeding
5/3- NT scan- both babies look healthy and no SCH One very squirmy wormy and one quiet bean!
6/22- level II U/S- Team pink! Choroid plexus cyst on baby b
7/20- 2nd level II U/S- no more CPC! Thank God
EDD 11/17/12
31 weeks 1 day 9/16/2012- Kendall Lynn and Kayla Lynn arrive early! Will be in the NICU for a while but are doing very well thank God!
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  #2  
Old 05-27-2011, 10:41 AM
MomMe's Avatar
MomMe MomMe is offline
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Posts: 20
Quote:
Originally Posted by Lilyrose1
Hey everyone! Anyone out ther with PCOS who has taken depakote in the past? Just curious since they think there is a link, and I was on it for ten years and developed PCOS in that time period. Just wandering if anyones in the same boat. Thanks!

Lilyrose,
I haven't taken Depakote, but I started taking Trileptal (which is very similar) in 2009, and I was just diagnosed with PCOS in April. I wonder if there is a link. I've heard the research has found some pretty strong evidence that there is a connection. Oddly enough, I've had to wean off of the Trileptal while trying to get pregnant because it may cause birth defects, and since I've stopped taking it my PCOS symptoms have decreased.

Wishing you and
__________________
**********
ME: 36
DH: 30


Our 4-legged babies
Bond 3 y/o boxer
Kaya 3 y/o boxer

Used NuvaRing prior to February of 2009,
after stopping Birth control.... never saw
Ironically I was an egg donor when I was in grad school, the family had two sets of twins.

TTC since February 2009
Final DX PCOS in April 2011


Started Provera April 23, 2011 X 5 days
Clomid Round #1 early May

50 mg Clomid Day 5-9
Waiting on a (+) OPK... it didn't happen

Round #2 comimg up... skipping the Provera this cycle came all by herself.
100 mg Clomid Day 3-7
Got my (+) OPK
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  #3  
Old 05-30-2011, 12:24 PM
Lilyrose1's Avatar
Lilyrose1 Lilyrose1 is offline
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Join Date: May 2011
Posts: 219
It's just crazy that we're prescribed medications for something, and they can affect our fertility. I'm glad that you have returned to normal after stopping. That's great new!!! My experience was the same with depakote as far as stopping for a planned pregnancy, and finally having regular periods.
__________________
Married 3 years
TTC 2 years
Me 33 PCOS
DH 33 SA good
DD 12 Jaleen Rose(from previous relationship)
Lily, Marbles, Princess, and Eddie

Insurance only covers 3 cyles iui or ivf, so...
ivf#1
8/7/11 Transferred 1 perfect blast-
9/21/11 Loss of HB at 9 weeks - Devastated
2 snowbabies

Feb. FET
2/28- ET- 2 blastocysts
3/23- US 2 lil' peanuts & 2 lil' h/b's!
4/2- SCH with bleeding
5/3- NT scan- both babies look healthy and no SCH One very squirmy wormy and one quiet bean!
6/22- level II U/S- Team pink! Choroid plexus cyst on baby b
7/20- 2nd level II U/S- no more CPC! Thank God
EDD 11/17/12
31 weeks 1 day 9/16/2012- Kendall Lynn and Kayla Lynn arrive early! Will be in the NICU for a while but are doing very well thank God!
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  #4  
Old 02-22-2012, 01:12 PM
blackdogmama's Avatar
blackdogmama blackdogmama is offline
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Join Date: Dec 2010
Posts: 23
I have!

Hi - I just made this connection. I was diagnosed with bipolar 4 years ago. During the first year, I suffered from severe insomnia. My psyche put me on all sorts of things to sleep - for a few months, one of them was Depakote. About a year later, having improved my mental health immensely, I went off birth control to start trying. I had no period for months and finally got in to see a RE. The ultrasound showed PC Ovaries but all I really had to show for it were some skin breakouts.

So now I have a 6 month old son after trying Clomid and Femara for ages and miscarrying once. We finally did injectables. First month on them I got pregnant with Leo.

I literally just stumbled upon the Depakote info yesterday while googling something else about PCOS. I always thought it was weird that I'm slender, have no blood sugar issues, no hair overgrowth, etc. What scares me though is that some things I've read links bipolar itself with PCOS which just seems crazy to me. My doctor is out of town but I can't wait to hear what he has to say when he gets back. Since Leo's birth I have had two spontaneous periods but I'm going to go back on the Ring with the next one. Maybe the PCOS is reversing after pregnancy and recovering from the Depakote? I don't know. What are your thoughts?
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Me, 29, PCOS, thin cyster, blood sugar fine
DH, 33, perfect
mama to black lab/pit mix, Clyde
TTC for 18 months
2010 - 4 rounds Clomid - 1
Ended in chemical at 5 weeks
2 rounds Letrozole + IUI - 2
12.14.2010 - First Letrozole + Menopur + IUI Cycle
At least 3 follies that looked like they were going to be ready to go. Hopeful.
13 dpiui - !!!!
First beta - 46
Second beta - 127
Baby boy due 9/6/2011
Leo Pete born 8/16/2011 - 3 weeks early!

Last edited by blackdogmama : 02-22-2012 at 01:59 PM.
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