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You might have more responses on the IVF part of the board under infertility treatments.
I think it depends upon whether its an egg quantity or an egg quality issue. The former means its harder to get pregnant, but the eggs that make it through are likely to result in a sustainable pregnancy. That was my issue. The quality is a bit tricker as it means some of the eggs may not be strong enough to let the pregnancy be viable. FSH is an indicator of quantity, not quality. Quality they can usually only tell after they've done a retrieval or if you've had a lot of miscarriages. Quality and age are strongly correlated. For example, I only had 4 eggs retrieved for IVF which is VERY low. But 3 of them fertilized and lived to transfer day which means they were all good quality. On the other hand my good friend had 20 eggs retrieved which is really high but not a single one survived to the third day. She had a lot of problems with her first pregnancy (almost miscarrying) and miscarried her second kid. That's more of an issue of quality. However, she does have a kid through IVF.
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Me: 32 DH: 37 TTC: 2 years before success Dia: PCOS, Endo, FSH ranging from 12 to 18 Treatments: 4 failed AI cycles, lap for endo First IVF attempt: May 2008 Beta #1: 5/25/08 HCG=246Anatomy scan: 09/09/08 It's a GIRL Brenna Catherine born 1/16/09 |
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Hi Jenn,
I understand how you feel. Like azariah said, it depends if it is a quality or quantity problem. If you are uncomfortable with your RE, you should find a new one. I had a higher FSH level than you, but I did get pregnant all on my own without even an IUI (IUI wouldn't work with FSH as high as mine). The pregnancy ended in m/c and after a D&C and lab work, it was determined that there was a heart problem and we (along with our RE) felt like it was a qualit issue too. Our RE always told us that it could happen and everything could be okay. He gave us a 3% chance of that happening. We decided to do donor and I am so glad we did. We are now pregnant (13 weeks and 2 days)!!! It was a difficult decision and a very personal one. I know it isn't for everyone. Good luck in you future pregnancy (it will happen for you) and I hope everything works out for you!
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Natalie me-29 POF Extra high FSH of 51 ![]() DH-29 Perfect 12/2008 started the IVF w/DE process 3/1 with hpt all on our own!!!!3/19 second u/s- Saw a fetal pole and heartbeat (only ~50bpm so doctor is worried) Please God, help my baby grow. 4/1 D&C Heartbeat has been gone for two days ![]() 7/2008 Starting DE IVF process again 8/25- Started BCPs 10/12 ER- 19 mature eggs retrieved- 12 for us 7 for the other couple 10/13- 8 fertilized 10/17- ET transferred 2 blasts and 2 frozen 10/24- very faint positive on a HPT 10/27- Beta 269!!! ![]() 10/29- Beta 707!!!! 11/7- U/S saw Sparkle on the screen. Too early for heartbeat. 11/13- U/S Looking good Sparkle! 127 bpm 11/19-U/S 160 bpm, 11/26-178 bpm, 12/10 183bpm 12/30- 156 bpm ![]() |
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Jen
Get a new RE, after 2 IUI's no doctor pushes a 30YO woman to IVF unless they have some sort of ulterior motive. AND There is no way at your age your eggs are 'just bad' with no scientific backing. Having one miscarriage is so very common that millions of women have them everyday and don't even know they are having them! That is no reason to go to IVF at this juncture.
Keep doing IUI's. Focus on getting yourself in perfect health by eating right, sleeping good, taking your folic, prenates, etc. and after you have given this at least 6 months to a year, then think about IVF. I wish you the very best and please get a new RE... ![]()
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![]() ![]() ![]() ![]() ![]() Me-41 (High FSH) DOR DH-27 (perfect) 2 best friends X & ZZ DS - Bo Jordan 20YO TTC since March 2006 ------------- 5-31-9 CD 28---->BFP 6-1-9 HCG--->15 DPO 287 6-9-9 HCG--->22 DPO 4637 6-18-9 OB APPT. We have a HB! 6-25-9 HB 136 slightly irregular sac 7wk3d6-30-9 HB 140's!! 7-10-9 Baby's OK! HB 140's 9wk2d (+-3d) It's a Girl! 8-26 Amnio- no it's not it's a BOY! 9-9 AMNIO --->OK DD: 2-8-10 ------------- Guess and win! http://www.expectnet.com/games/BirthdayStats |
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Quote:
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TTC 10months with current husband. 3 years with previous ME 35 tubal problems DH 40-Low sperm morphology 2004 Ectopic pregnancy 5/08 IUI-chemical pg first beta 1050 7/08--IVF canc poor reponse 8/08--IVF converted poor respons 11/26 IVF (1) 6cAA, (2) 8cAB (3) 8cBA none to freeze pending Beta 12/05 11/29-12/3--Neg Hpt 12/5/08++hpt #1 Beta 32.7 9dp3dt 12/08/08--#2 Beta 182 12dp3dt Prog >2012/10/08 -#3 Beta 578 14dp3dt Prog 19912/15/08--#4 Beta 4359 19dp3dt ![]() 12/22/08-6w1d u/s HR 117bpm Beta 16,800 12/31/08-7w3d U/S-HR 164 CRL 12mm Beta 38,600 1/9/09-8w4d HR 174, CRL 18.1mm Beta 81,000 1/20/06- 10W2d HR 180, CRL 34.2 MM 2/10/09-- 13W3d CRL 71.5mm 8/18/09 @ 1104 Matthew was born 8 pounds and 20 1/2 inches long. |
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Just commenting
Ladies,
I also have DOR and my RE really wanted us to keep going with IUI's due to age. She thinks that although my egg quantity is not great - the quality she thinks is fine! Having said that we have decided after 3 failed IUI's to move on to IVF. We felt like with this condition things would not improve the longer we waited, so we wanted to try IVF while we still had some - hopefully - good quality eggs!?!! My RE seems really confident and has not mentioned donor eggs to me at all! Although when I read online about DOR that is ALL I see! Jen, I would say look for a new RE - you need someone who is positive!!! Oh well, glad I saw this thread! Infertility is so difficult and at times you can feel so alone! Nice to hear from people going through the same things! Good luck to everyone!!! ![]()
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Carrie TTC 2 yrs Me: 31 (Blocked tube, DOR) DH: 33 (Perfectly fine) Zeke(english bulldog), our only baby for nowWorking with RE since Jan. 2008 [font=Georgia][size=1]Left Tube Blocked Got after surgeryMiscarried at 8w (extra chromo.) 1st IUI with Clomid and inject. scheduled for 8/21/08 2nd IUI with Clomid and inject, scheduled for 9/21/08 Cysts!!! on BCP for Oct! 3rd IUI with Femara, menopur, and ovidrel, scheduled for 11/17/08 12/23/08 Started Lupron 1/2/09 Baseline U/S and B/W CYCLE CANCELLED - Lupron over-supressed Moving on to EPP 1/19/09 B/W 1/29/09 Ganirelix & Estrogen Patches 2/13/09 ER (12 eggs, 8 mature, 8 fertilized) 2/16/09 ET (transferred 2 - 8 cell, grade 1 embryos) 2/21/09 B/W -progest. test 2/28/09 BETA beta 1333/2/09 2nd BETA beta 3083/16/09 1st u/s One Healthy Heartbeat! 3/23/09 2nd u/s Looking good 4/17/09 1st OB appointment m/c
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Hi Jen,
I'm with my third RE and finally got a confirmed diagnosis of DOR. My highest day 3 FSH was 24.3 and a day 10 of 36 during the CCT. Did you RE test your AMH? After testing my AMH (which was 0.1 and in the "undetectable" range) my RE gave us a 1% chance of ever conceiving with my own eggs even with fertility treatments. He strongly advised us to go with donor eggs but he said he would keep doing IUIs with us if it is important to us. He doesn't think my quality is bad, just quantity, but he said the only way to know if the quality is bad would be if they retrieved some as per an IVF protocol. I'm with my third RE for a reason. The first one was TERRIBLE and didn't even tell me I had high FSH or that there was anything besides endo wrong with me. He put the cause on my DH's sperm. We had a gut feeling that he wasn't telling us the whole truth and boy were we right. Our second RE was very kind and told us that the first RE was not giving us the complete story. DOR is not only an infertility issue but you are begininng to enter menopause and it can impact your health too (need to watch out of osteoporisis, heart disease, etc.). We moved to another state and ended up with our third RE who is one of the best in the country. He agreed with our second RE and ordered more tests. My advice would be to listen to your gut. If you think that your RE isn't right than he/she probably isn't. We put so much pressure on ourselves with this IF journey and sometimes we don't want to deal with the extra time it will take to switch RE's, retest, etc. that we keep with the old doc our gut is telling us to leave. Donor eggs is a very personal decision. We first reacted very negatively and I couldn't imagine using a DE. After letting all this sink in we have come to realize it is a great option and we are lucky to live in a time where it is available to us. We still don't know what we are going to do but we are open to it all. We are now exploring infant domestic adoption, DE, and I'm having one more IUI with very high gonal F doses. Best of luck to you! ![]() ![]() ![]() ![]()
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Danielle - TCC 7 years Me: 33, DOR, high FSH, >0.1 AMH & endo (RE said less 1% chance I can conceive with my own eggs) DH: 37, count, morph, and motility low. Motility is improving with vitamins. TCC since Aug. 2001 - BFN every cycle 4 IUIs (3 medicated), all BFN Laparoscopy; 10/23/07 - cleaned up stage II endo Moved to the fertility friendly state of MA this summer and we have a great new RE. IUI #4: 10/25/08 & 10/26/08 Back to back IUIs (Clomid 100 mg, Ovidrel, Crinone). Beta 11/10/08. BFN IUI #5: 1/9/09 & 1/10/09 Back to back IUIs (600 IU Gonal-F, Ovidrel hcg trigger, Crinone 8%), 2 follies Beta 1/26/09 BFN Natural Cycle TOTAL SHOCK (stopped trying - did everything I wasn't supposed to) 4/11/09: on HPT 4/13: Beta 68 4/15: Beta 125 4/23: Beta 1418 5/8: U/S showed no HB, measured too small 5/14: U/S showned no HB and still too small 5/15/09: D&C ![]() 2 furry dog children ( Mickey & Mudge)
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thank you so much for your replies!
chickycran- good luck with your next iui-I hope this is THE one for you ccandcc- good luck with your ivf cycle! yamensleh- goodluck with whatever you decide to do next. renni- thanks for the advice and encouragement. I think we will seek a second opinion after all. Hopefully it will go well! natalie- I am so sorry about your m/c. Congratulations on your pregnancy now! azariah- thank you for the advice on quality vs quantity. I hadnt really thought about it that way. RE has made no mention about that-so frustrating!!
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Jen me-30- probable DOR- RE thinks maybe i have poor eggs DH- 35-no sperm!! high FSH of 28 our furrbabies: Auggie and Star (dogs), Mr. Toes, Lily and Diesel (kitties) ttc x 4 years Nov. 5th- TESE results: sperm found!!! IVF #1- cancelled after only 2 follies made IVF #2 6/2 flare protocol-5 follies iui# 1 with DS- oct 6 (21.8 mil post wash) iui#2 nov 5th (19.6 mil post wash) ![]() 12dpiui- hpt !!!! Dec.9th first US empty sac 12/26- cytotec to induce miscarriage 3/14- iui#3 25.5 mil swimmers ![]() 16dpiui beta #1 ... 424!! - please let this one be ok!! 4/6 beta #2 23dpiui 6,862!! 4/14 first US 6w3d-sac measuring 5.5 week 4/21 sac still empty- another blighted ovum 4/22 cytotec again No more treatments. We are ready to move on. Happily pursuing domestic infant adoption Oct. 20,2009 officially active with our agency and waiting for a baby!! ![]() |
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If you do a yahoo search on dimished ovarian reserve, you will find quite a few docs are of the mindset that the quantity is reduced, not the quality!
I'm in the same boat, and am coming to the conclusion that I might have to go through some more cancelled cycles to get the batch I need! To me that's better than going to retrieval without enough to give me a good chance.
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Me: 33 DH: 35 Married 14 years in December. Furbaby Zoey 7 year old Rotti/Lab mixTTC #1 IVF 1 Cancelled due to poor response IVF 2 Also pretty poor responseIVF 3 Maybe, we'll see what another RE thinks **Appt with current RE 12/8 **Appt with another RE at Cleveland Clinic 1/8 Check out my blog! http://chadandkirsten.blogspot.com/ |
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question
I'm following this thread with personal interest: I am 35, FSH 5.8, but diminished ovarian reserve; on aggressive stimulation (450 Follistim + 150 Menopur), I only managed to get two, maybe three mature follicles. I have two questions:
1) Has anyone else been told that with fewer than 4 follicles it's not worth doing IVF? It seems to me that since the success rates of IVF are higher than IUI, it would be worth going through retrieval/transfer for that, but my dr. says they don't do that. 2) Any sense of how many ART cycles it would take for us to legitimately have given it our all? I know this is a personal decision, but we've done 2 IUI cycles, and I know people do much more than that, but I don't want to be either overly optimistic or prematurely pessimistic. Thank you! |
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Jen,
To answer your question "I was wondering if anyone else out there was told by their RE that egg donor was their only option and you went on and had a baby with your own eggs?"..... YES! As I wrote in another blog, I was 28 and my highest FSH was 14.5 (I go by the highest # b/c the studies show that is the most accurate reflection of your true ovarian function) and my AFC's was 3 (right ovary) and 6 (left). I did clomid x 2 mos, then follistim with IUI x 1 month, then IVF (with ICSI and had ~10 follicles, 4 mature eggs, 2 embryos transferred), then 3 mos of follistim with IUI's, then IVF (13 follicles, 8 mature eggs, ICSI, 2 embryos), then another IUI... didn't get pregnant. I then had a phone consultation with a RE at CCRM (Colorado Center of Reprod Medicine, the #1 IVF center in the country) and he said that I only had a 10-15% chance of having a baby with IVF and that he'd recommend I go to egg donor... 3 weeks after that conversation I got pregnant on my own, out of the blue (at the age of 30)! The only fertility med I was taking was DHEA 25mcg twice daily. I now have a gorgeous 6 month old son. So it CAN happen! Now I'm just hoping it'll happen again. This blog gives me hope. Despite my RE's discouragement, I think I'm going to go back to trying IVF... even though it didn't work the first 2 times, I'd rather do that then keep trying on my own (which hasn't worked the past 6 months). Stay positive- it really CAN happen! |
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Hi everyone! I am glad to have found you. I am 30 and in the 2WW of IUI #9. My husband and I are considering doing IVF this summer, and I was wondering, do any of you know if IUI and injectibles is a better option than IVF for those with DOR? We are very unsure of what to do next.
We don't have money for treatments over and over again, so we need to move on to something more aggressive with better success rates, but we also don't want to sink so much money into IVF if IUI's are going to be just as good an option. Also, how can you determine if it is a quality or quantity issue? I have never had a miscarriage. My last AFC was 18, but only 2 (barely) were mature at IUI. Thanks everyone!
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Me-30 - diminished ovarian reserve, slightly hypothyroid DH-30 - slight levels of abnormal morphology, low testosterone Parents of two wonderful pups 09/03 - married 05/07 - started TTC Treatment History: 03/08 - HSG all clear 05/08 - 07/08 - 3 IUI's w/ Clomid, Ovidrel = BFN 08/08 - took the month off, natural cycle 09/08 - 11/08 - 3 IUI's w/ Femara, Ovidrel = BFN 11/19/08 - confirmed diminished ovarian reserve; bloodtest found I am slightly hypothyroid 12/08, 1/09 - took a much needed BREAK!!! 2/09 - IUI, Femara, Bravelle, Ovidrel = BFN 3/09 - EFORT test: still only 2 follies, IUI... 3/27/09 - 4/1/09 - 16 dpiui - 1st beta = 358 4/3/09 - 18 dpiui - 2nd beta = 737 ![]() 4/22/09 - 7 week u/s: HB 152! 5/7/09 - first obgyn visit 6/22/09 - HB 147 7/10/09 - 18 week anatomy scan
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I was able to conceive with my own eggs and I had DOR. It took several months of Chinese herbs, acupuncture and meditation.
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