[30somethingmom]

Is anyone familar with a Luteal Phase Defect? I know someone whose doctor suggested she be tested for this. What is it exactly and how does it affect infertility? Also, what is the recommended treatment?

Thanks!

[slobin]

Luteal phase defect (LPD) means that the post-ovulatory phase of the cycle is insufficient- usually shorter than 11 days or so. Usually this is from poor ovulation/low progesterone and the corpus luteum (the remains of the follicle that egg was released from) breaks down to early to allow implantation. In a normal cycle the corpus luteum continues to secrete estrogen and progesterone for close to 14 days to allow for implantation. If this isn't happening, you have LPD. The most common treatment for this is Clomid or injectible drugs. By creating "super-ovulation" the luteal phase is strengthened and hormones boosted.

Tests for this would include a progesterone test in luteal phase (about 8 days after O) and/or an endometrial biopsy to check lining to see if it's properly prepared for implantation.

Hope this helps.