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  #1 (permalink)  
Old 01-20-2008, 08:32 PM
john john is offline
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Join Date: Jan 2008
Posts: 4
Agglutination

Hello Everybody,

I've been diagnosed with severe agglutination, and obviously, we've had problems conceiving. Does anyone know of any medication or anything else for that matter. Any input would be much appreciated .

Thank You
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Old 01-21-2008, 06:39 AM
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Teagan873 Teagan873 is offline
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Posts: 333
Hi John...Vitamin C (500-1000 mg per day) can really help agglutination. Have you or your wife been tested for sperm antibodies? I have read that these antibodies can thicken the sperm as well.
__________________
Carie
Me - 35 = Poor egg quality/DOR/Poor Stimmer/High CD3 FSH and Estrogen (bla...bla...bla)
DH - 36 = Low & slow
TTC >3 years
Kitchen Sink Info:
#1 IVF/ICSI & AH = BFN
#2 IVF/ICSI & Thyroid meds = BFP (Ectopic)
#3 IVF/ICSI & Metformin 03/07 = BUST
02/02/08 = Started taking Royal Jelly & Bee Pollen in honey (it worked for me!!)
03/03/08 = 100 mg Clomid w/ DS (PreSeed+Instead Cups) = BFN
04/02/08 = 100 mg Clomid w/ DS (PreSeed+Instead Cups) = BFP
1st Beta --> 05/02/08 = 232 (15dpo)
2nd Beta --> 05/05/08 = 846
3rd Beta --> 05/07/08 = 1874
U/S --> 05/13/08 = (5w6d) Saw heartbeat/got pictures

U/S --> 05/22/08 = (7w1d) Heard heartbeat/141 bpm (measure 7w)
U/S --> 06/02/08 = (8w5d) Saw baby moving arms and legs/179 bpm (measure 8w5d)
OB ---> 06/06/08 = (9w2d)
Anatomy Scan --> 08/20/08 (20w) It's a BOY!!

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Old 01-21-2008, 06:14 PM
john john is offline
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Posts: 4
Vitamine C is great, however, in megadoses. I've read that up to 20 grams a day will cure it. I've been taking about 8 grams a day for one month and had a FANTASTIC improvement, however the problem takes a while longer. I'm going for another analysis, and hopefully I'll see another significant improvement.
My count and morphiology are very high, but useless in the end because of the aggulitation, therefore poor motility.
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Old 01-21-2008, 06:29 PM
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jencat215 jencat215 is offline
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Posts: 9,565
Good luck on your next SA. Hopefully the Vitamin C has helped. I agree with Teagan about getting testing for anti-sperm antibodies.
__________________

Me: 35 MTHFR hetero, no other issues
DH: 33 Perfect
Etienne , Jake , Sam (cats) Maggie (iguana)
TTC #1: 2 yrs
2 m/c (Aug '06 and Jan '07), 1 ectopic pg (lost left tube)

5 IUI's

5/27: beta #1: 716!!!! (17dpo) Natural cycle!
5/29: beta #2: 1885!!!!
6/1: early u/s-1 sac/yolk
6/9: u/s#2-saw and heard hb! 114 bpm. Measuring 6w2d
6/17: u/s #3- hb 154 bpm. Measuring 7w3d
7/1: u/s #4- hb 161 bpm. Measuring 9w4d
7/9: first OB appt.-u/s #5- hb 152 bpm. Measuring 10w4d
7/17-NT scan-everything looks great! Measuring 11w6d
8/14-quad screen (quick gender check):
IT'S A BOY!!!
9/4- Level II u/s. Baby is doing great! Measuring 5 days ahead.





check out my website! www.glassphusions.wordpress.com
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Old 01-21-2008, 07:17 PM
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Teagan873 Teagan873 is offline
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Join Date: Jan 2007
Posts: 333
Wow John...up to 20 grams (20,000 mg) is unbelievably high. I just did a quick google search too and I don't see any websites suggesting doses over 1000 mg. Does your doctor know you are taking that much vitamin C?

If you don't mind me asking...what do you mean by "fantastic" improvement? My husband has a similar issue and now I'm wondering if he's not giving me all the details or if he's taking a high enough dose of vitamin C If you can find the info about using high doses to treat agglutination...will you post the website?
__________________
Carie
Me - 35 = Poor egg quality/DOR/Poor Stimmer/High CD3 FSH and Estrogen (bla...bla...bla)
DH - 36 = Low & slow
TTC >3 years
Kitchen Sink Info:
#1 IVF/ICSI & AH = BFN
#2 IVF/ICSI & Thyroid meds = BFP (Ectopic)
#3 IVF/ICSI & Metformin 03/07 = BUST
02/02/08 = Started taking Royal Jelly & Bee Pollen in honey (it worked for me!!)
03/03/08 = 100 mg Clomid w/ DS (PreSeed+Instead Cups) = BFN
04/02/08 = 100 mg Clomid w/ DS (PreSeed+Instead Cups) = BFP
1st Beta --> 05/02/08 = 232 (15dpo)
2nd Beta --> 05/05/08 = 846
3rd Beta --> 05/07/08 = 1874
U/S --> 05/13/08 = (5w6d) Saw heartbeat/got pictures

U/S --> 05/22/08 = (7w1d) Heard heartbeat/141 bpm (measure 7w)
U/S --> 06/02/08 = (8w5d) Saw baby moving arms and legs/179 bpm (measure 8w5d)
OB ---> 06/06/08 = (9w2d)
Anatomy Scan --> 08/20/08 (20w) It's a BOY!!

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Old 01-21-2008, 08:57 PM
john john is offline
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There are a few sites, just indicate "megadoses of vitamine C for agglutination" here is one site citing a study at the University of Texas.

Doctor Yourself: Natural Healing ... - Google Book Search
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Old 01-21-2008, 09:18 PM
john john is offline
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Join Date: Jan 2008
Posts: 4
My urologist did the math and calculated that since my count is very high, even though I have about 20% motility, it is still significantly high, therefore, he said keep on trying. I asked him about megadoses of vitamine c, but since prescribing vitamines is not a part of his protocal, he didn't touch the issue. I am taking the bull by the horns on my own. I've looked into the side effects of megadoses. Regarding vitamine c, it is water soluable, not manufactured nor retained by the body, hence no toxins. What the body does not need it will discard. If you have kidney problems or stones, some literature states that caution should be taken or drink plenty of water.

Regarding my results, based on gradient sperm washing, (I'm trying artificial insemination), in one month the numbers jumped astronomically. Under gradient sperm washing, the parameters are strict.
They require at least one million of the best swimmers. Hope I've added some hope to someone.
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Old 01-22-2008, 04:56 AM
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Teagan873 Teagan873 is offline
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Join Date: Jan 2007
Posts: 333
Hmm...interesting. You know...come to think of it...we are using (known) donor sperm in a couple months and our donor takes (what I call) a ton of Vitamin C. He takes Emergen-C (powered drink) in the morning, a multi vitamin, Fertility Blend at night, plus everything he consumes in a day that has it. When he went to get his SA done it was off the charts and they pretty much stopped counting. Now I'm stating to wonder! Keep me posted on what your results are this time around...sounds promising! Have you and your wife had the antibodies tested?
__________________
Carie
Me - 35 = Poor egg quality/DOR/Poor Stimmer/High CD3 FSH and Estrogen (bla...bla...bla)
DH - 36 = Low & slow
TTC >3 years
Kitchen Sink Info:
#1 IVF/ICSI & AH = BFN
#2 IVF/ICSI & Thyroid meds = BFP (Ectopic)
#3 IVF/ICSI & Metformin 03/07 = BUST
02/02/08 = Started taking Royal Jelly & Bee Pollen in honey (it worked for me!!)
03/03/08 = 100 mg Clomid w/ DS (PreSeed+Instead Cups) = BFN
04/02/08 = 100 mg Clomid w/ DS (PreSeed+Instead Cups) = BFP
1st Beta --> 05/02/08 = 232 (15dpo)
2nd Beta --> 05/05/08 = 846
3rd Beta --> 05/07/08 = 1874
U/S --> 05/13/08 = (5w6d) Saw heartbeat/got pictures

U/S --> 05/22/08 = (7w1d) Heard heartbeat/141 bpm (measure 7w)
U/S --> 06/02/08 = (8w5d) Saw baby moving arms and legs/179 bpm (measure 8w5d)
OB ---> 06/06/08 = (9w2d)
Anatomy Scan --> 08/20/08 (20w) It's a BOY!!

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