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Old 05-01-2007, 10:17 AM
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cathmich1 cathmich1 is offline
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Question Chromosomal Abnormalities Testing

Hi,
I just had my post-IVF consultation with my RE, and she says the next step would be for me to go through stims again (ugh) and do another IVF cycle (ugh), but this time remove 1 cell from each egg and analyze it for chromosomal abnormalities. I think it is called a PGD test. This will show if a number of my eggs have chromosomal abnormalities, and this will then allow us to pick the best eggs that do not have abnormalities and use them in the IVF cycle.

Has anyone had this test, and if so, do you feel it is worth trying? I have some concerns about removing a cell from each egg.

We are definitely not ready to do another IVF cycle anytime in the near future, if ever. However, this was interesting to hear, and I would like to know if anyone has gone this route and what they thought of it.

Thank you!
Cathy
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Old 05-01-2007, 10:24 AM
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I personally have not had this done with my embryos but DH and I did undergo chromosomal testing after our failed IVF. There are a few people on this forum who have done PGD and we've got great success. I believe that we have two women who had 100% implantation success. But I do know that we've had one failed cycle too. It's worth looking into and I'd say it's worth it.
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Old 05-01-2007, 12:30 PM
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LineaLI LineaLI is offline
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We have friends who are both carriers for CF and for them to have a baby there is a 50 % chance it will be a carrier of CF 25% OK and 25% affected by CF. They will probably to PGD to avoid having a child with CF. It is a lot to think about because you have to understand what you want to do with the information. Just wanted to share what I know about the process. Ask your doctor what he thinks they testing could show for you as a couple.
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Old 05-01-2007, 02:18 PM
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cathmich1 cathmich1 is offline
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Jen and Linea,

Thank you both for your information. The funny thing is that we would not be undergoing the testing to look for any specific genetic condition - neither of us have any problems in our families. The reason for the testing would strictly be to eliminate the chromosomally imperfect eggs and only use the eggs without a defect. She said this would improve our odds of success dramatically. Jen - how did you do the chromosomal testing without doing it during an IVF cycle? I would be very interested in this type of testing rather than having to mess with my embryos.

I think it seems a little odd for our doctor to suggest that we do this testing when there is no family history of disorders for either of us- isn't that the reason that most people do this type of testing? Has anyone that you have heard of done this type of testing just to eliminate the defective eggs and have a better chance at success?

Thank you again for your responses. This is all so confusing!

Blessings,
Cathy
__________________
me-36 - Hashimoto's Thyroiditis
dh-37 - perfect!
unexplained infertility
ttc 3 years
5 failed IUIs w/Clomid
Ist IVF Sept. '06
FET 3/26/07 Transferred 4 embryos
Moving on to adoption

Last edited by cathmich1 : 05-01-2007 at 02:21 PM.
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