Family Forums
Parenting Forums
Pregnancy Forums
Adoption Forums
Fertility Forums



Register FAQ Members List Today's Posts Calendar Search Today's Posts Mark Forums Read
Forum Categories
User Name
Password

Reply
 
Thread Tools Search this Thread Display Modes
  #1 (permalink)  
Old 10-31-2008, 04:03 PM
LGB LGB is offline
Senior Member
 
Join Date: Aug 2008
Posts: 895
Immature Eggs

I am wondering for those of you who got a lot of immature eggs during your IVF cycles, do you ovulate regularly on day 14 and have 28 day cycles (non-medicated)?

Both IVFs I have had so many immature eggs and I truly believe that this is linked to my strange cycles when not on meds....I don't ovulate until Day 22 and get my period on Day 42. Therefore, my eggs take a LONG time to mature/my estrogen doesn't rise like it should. And this would explain why my eggs were so immature during IVFs and why my estrogen was never as high as it should of been for the # of eggs produced.

Does any of this make sense and does anyone fit in this category with me?

My acupuncturist seems to think that herbs can help regulate my cycle and get it back on track, hence ovulating earlier and having my estrogen be at the level it should be at, at the right time in my cycle.
__________________
Me: 32, Stage 2 Endo, Hereditary Egg Quality Problem & Family History of IF all around!
DH: 37, Perfect-thank goodness one of us is!
TTC #1 for 2 years-6 months on our own, 3 months Letrozole with OB-BFN, 2 IUIs with Letrozole-BFN, 2 IVFs with my own eggs-BFN, DE IVF Fresh Cycle-BO m/c

FET August 31-2 4AA blasts
Beta #1 14dpo 196, Beta #2 16dpo 470, Beta #3 23 dpo 7,019
1st US at 6w1d bc of bleed (SCH found, less than 1 cm)-singleton measuring 5w6d HB 120bpm
2nd US at 7w1d-SCH 1cm-baby meausuring 6w6d HB 151bpm
3rd US at 7w5d-SCH still 1cm-baby measuring 7w5d HB 169
4th US 9w1d-SCH going away, baby measuring 9w1d HB 182
Released to OB! Stopped all meds, woo-hoo!
5th US 10w1d-SCH GONE! Baby measuring ahead at 10w3d HB 167
1st OB appt. 10//29-baby a busy bee!
2nd OB appt. 11/5-baby having a party in there! 12w appt.
3rd OB appt 12/1=16w appt.
E.D.D. May 19th, 2010!!



Reply With Quote
Click Here to Learn More
  #2 (permalink)  
Old 10-31-2008, 07:11 PM
Waiting4thestork's Avatar
Waiting4thestork Waiting4thestork is offline
Member
 
Join Date: Sep 2008
Posts: 113
I am the same way. Read my signature, my 1st IVF I had only 3 mature eggs and of those none made it to ET. I do not Ovulate regular either! Infact clomid at 150mg didnt even make me Ovulate. I do not have a period either. Hope this helps!
__________________


for God to bless us

Me: No problems known
DH: Perfect

Sept: IVF #1
Follistem 225
Menopur 75
ER 15 follicles
12 eggs
only 3 mature
2 fert with ICSI
NO embies to go to ET

Began birth control pills waiting for

October IVF
RE changed my medication dose
300 follistim
150 menopur
10-6 last birth control pill
10-9 u/s baseline test to begin stim
10-15 u/s showed 15 follies!
10-17 u/s showed 18 follies!!!!
10-19 u/s showed 19 follies!!!!
Biggest 1 was 23mm
ER 10-22
19 follies 19 eggs 7 mature ALL fert with ICSI!
ET 10-26 My dr does 4 day ET- transfered 3 embies 2 good quality 1 poor
BETA 11/6

POAS 6/1,2,3 VARY faint
POAS 6/4 DARK
PLEASE GOD BLESS US
Reply With Quote
  #3 (permalink)  
Old 10-31-2008, 07:50 PM
LGB LGB is offline
Senior Member
 
Join Date: Aug 2008
Posts: 895
Thanks for sharing. It looks like your 2nd IVF has gone so much better with a lot more matures. What was your estrogen and how big were your follicles when they triggered?

What does your RE say about your not ovulating and no periods? That sounds very PCOS like...

I do ovulate each month and get my period each month, but it's always 22 days and 42 days. So my eggs are poor quality bc my ovulation is so off...
__________________
Me: 32, Stage 2 Endo, Hereditary Egg Quality Problem & Family History of IF all around!
DH: 37, Perfect-thank goodness one of us is!
TTC #1 for 2 years-6 months on our own, 3 months Letrozole with OB-BFN, 2 IUIs with Letrozole-BFN, 2 IVFs with my own eggs-BFN, DE IVF Fresh Cycle-BO m/c

FET August 31-2 4AA blasts
Beta #1 14dpo 196, Beta #2 16dpo 470, Beta #3 23 dpo 7,019
1st US at 6w1d bc of bleed (SCH found, less than 1 cm)-singleton measuring 5w6d HB 120bpm
2nd US at 7w1d-SCH 1cm-baby meausuring 6w6d HB 151bpm
3rd US at 7w5d-SCH still 1cm-baby measuring 7w5d HB 169
4th US 9w1d-SCH going away, baby measuring 9w1d HB 182
Released to OB! Stopped all meds, woo-hoo!
5th US 10w1d-SCH GONE! Baby measuring ahead at 10w3d HB 167
1st OB appt. 10//29-baby a busy bee!
2nd OB appt. 11/5-baby having a party in there! 12w appt.
3rd OB appt 12/1=16w appt.
E.D.D. May 19th, 2010!!



Reply With Quote
  #4 (permalink)  
Old 10-31-2008, 08:11 PM
Waiting4thestork's Avatar
Waiting4thestork Waiting4thestork is offline
Member
 
Join Date: Sep 2008
Posts: 113
Quote:
Originally Posted by LGB
Thanks for sharing. It looks like your 2nd IVF has gone so much better with a lot more matures. What was your estrogen and how big were your follicles when they triggered?

What does your RE say about your not ovulating and no periods? That sounds very PCOS like...

I do ovulate each month and get my period each month, but it's always 22 days and 42 days. So my eggs are poor quality bc my ovulation is so off...

It has been that way my ENTIRE life! I am SUPER thin, have been tested for EVERYTHING, it is just my genetics! So with my fat index comp. he says that is why I am not having a period, and hence why I do not ovulate.

Yes, this cycle is MUCH better. I was pretty much just happy to make it to ET. I was so scraed I was going to have an egg issue this time again. My biggest before trigger was 23 or 24mm they said. Which I think that egg is actually inside of me right now! I think that was the best one for ET.

They upped my meds this last time, and I stim longer. Also did BCP when last time I didnt have to because I just came off an IUI cycle. So I think that may have helped also. I never asked for any of my blood draw #, but I wish I had.
__________________


for God to bless us

Me: No problems known
DH: Perfect

Sept: IVF #1
Follistem 225
Menopur 75
ER 15 follicles
12 eggs
only 3 mature
2 fert with ICSI
NO embies to go to ET

Began birth control pills waiting for

October IVF
RE changed my medication dose
300 follistim
150 menopur
10-6 last birth control pill
10-9 u/s baseline test to begin stim
10-15 u/s showed 15 follies!
10-17 u/s showed 18 follies!!!!
10-19 u/s showed 19 follies!!!!
Biggest 1 was 23mm
ER 10-22
19 follies 19 eggs 7 mature ALL fert with ICSI!
ET 10-26 My dr does 4 day ET- transfered 3 embies 2 good quality 1 poor
BETA 11/6

POAS 6/1,2,3 VARY faint
POAS 6/4 DARK
PLEASE GOD BLESS US
Reply With Quote
  #5 (permalink)  
Old 10-31-2008, 08:23 PM
LGB LGB is offline
Senior Member
 
Join Date: Aug 2008
Posts: 895
Do you know how many days of stims you did? I kept asking my RE to stim me longer bc I knew my eggs would be immature again, but my RE wouldn'. They were worried bc my progesterone was rising, which means I was getting closer to ovulation and my eggs could have been overlymature (No way of that!)
__________________
Me: 32, Stage 2 Endo, Hereditary Egg Quality Problem & Family History of IF all around!
DH: 37, Perfect-thank goodness one of us is!
TTC #1 for 2 years-6 months on our own, 3 months Letrozole with OB-BFN, 2 IUIs with Letrozole-BFN, 2 IVFs with my own eggs-BFN, DE IVF Fresh Cycle-BO m/c

FET August 31-2 4AA blasts
Beta #1 14dpo 196, Beta #2 16dpo 470, Beta #3 23 dpo 7,019
1st US at 6w1d bc of bleed (SCH found, less than 1 cm)-singleton measuring 5w6d HB 120bpm
2nd US at 7w1d-SCH 1cm-baby meausuring 6w6d HB 151bpm
3rd US at 7w5d-SCH still 1cm-baby measuring 7w5d HB 169
4th US 9w1d-SCH going away, baby measuring 9w1d HB 182
Released to OB! Stopped all meds, woo-hoo!
5th US 10w1d-SCH GONE! Baby measuring ahead at 10w3d HB 167
1st OB appt. 10//29-baby a busy bee!
2nd OB appt. 11/5-baby having a party in there! 12w appt.
3rd OB appt 12/1=16w appt.
E.D.D. May 19th, 2010!!



Reply With Quote
  #6 (permalink)  
Old 10-31-2008, 08:40 PM
okitoki's Avatar
okitoki okitoki is offline
Senior Member
 
Join Date: Jul 2008
Posts: 266
Hi, LGB. This past cycle I also had a lot of immature eggs... Although my unmedicated cycles are pretty short-- 26 days with ovulation occurring during days 12-14.

I wondered actually for me if the trigger of 5K iu was too low and also whether they triggered me too soon. I've done some research on the internet about immature eggs, but haven't really found anything definitive. I am very interested in this topic, so please let me know if you make any discoveries...
__________________
Me (38; Hashimoto's thyroiditis & DOR)
DH (40; normal)

IVF #1 - July 08
Antagonist protocol: 337.5iu Gonal F & Ganirelix
only 4 follicles; cancelled & converted to IUI on 7/18


IVF #1.5 - Oct 08
Antagonist protocol: 600iu Gonal F & Ganirelix
ER 10/13 - 11 eggs; 5 mature & ICSIed; 4 fertilized
ET 10/17 (4 day) - 2 morulae; 2 frozen
beta 10/31

IVF #2 - Jan 09
Antagonist protocol: 450iu Gonal F & Ganirelix
ER 1/12 - 8 eggs; 4 mature & ICSIed; 3 fertilized
ET 1/15 (3day) - 3 morulae
beta 1/29

IVF #3 - April 09
Microdose lupron protocol: 20units twice a day (4/7) + 450iu Gonal F (4/9)
ER 4/21 - 8 eggs; 5 mature & ICSIed; 1 fertilized
ET 4/24 - 3 transferred: 1 fresh plus 2 thawed from Oct 08 cycle
beta 5/8 AGAIN!!

******Finally changing RE******

7/17 one day workup at CCRM

ER 9/12 - 12 eggs; 9 mature & ICSIed; 7 fertilized
9/18 - FOUR blasts!! (never had blasts before)
Microarray testing being performed on blasts; results expected in six weeks
Reply With Quote
  #7 (permalink)  
Old 11-01-2008, 07:31 AM
LGB LGB is offline
Senior Member
 
Join Date: Aug 2008
Posts: 895
Quote:
Originally Posted by okitoki
Hi, LGB. This past cycle I also had a lot of immature eggs... Although my unmedicated cycles are pretty short-- 26 days with ovulation occurring during days 12-14.

I wondered actually for me if the trigger of 5K iu was too low and also whether they triggered me too soon. I've done some research on the internet about immature eggs, but haven't really found anything definitive. I am very interested in this topic, so please let me know if you make any discoveries...
In your case, it really does sound like they triggered too early and only 5,000 units instead of 10,000 sounds low. But, I'm not an RE here! he he

And I know it's tricky bc they have to make sure your estrogen is just right and that your progesterone doesn't rise too much too quickly, which can cause post mature eggs/ovulation.

I think my case is a little different since I ovulate so late, it's takes forever for my eggs to mature! ugh!
__________________
Me: 32, Stage 2 Endo, Hereditary Egg Quality Problem & Family History of IF all around!
DH: 37, Perfect-thank goodness one of us is!
TTC #1 for 2 years-6 months on our own, 3 months Letrozole with OB-BFN, 2 IUIs with Letrozole-BFN, 2 IVFs with my own eggs-BFN, DE IVF Fresh Cycle-BO m/c

FET August 31-2 4AA blasts
Beta #1 14dpo 196, Beta #2 16dpo 470, Beta #3 23 dpo 7,019
1st US at 6w1d bc of bleed (SCH found, less than 1 cm)-singleton measuring 5w6d HB 120bpm
2nd US at 7w1d-SCH 1cm-baby meausuring 6w6d HB 151bpm
3rd US at 7w5d-SCH still 1cm-baby measuring 7w5d HB 169
4th US 9w1d-SCH going away, baby measuring 9w1d HB 182
Released to OB! Stopped all meds, woo-hoo!
5th US 10w1d-SCH GONE! Baby measuring ahead at 10w3d HB 167
1st OB appt. 10//29-baby a busy bee!
2nd OB appt. 11/5-baby having a party in there! 12w appt.
3rd OB appt 12/1=16w appt.
E.D.D. May 19th, 2010!!



Reply With Quote
  #8 (permalink)  
Old 11-01-2008, 10:06 AM
Waiting4thestork's Avatar
Waiting4thestork Waiting4thestork is offline
Member
 
Join Date: Sep 2008
Posts: 113
Quote:
Originally Posted by LGB
Do you know how many days of stims you did? I kept asking my RE to stim me longer bc I knew my eggs would be immature again, but my RE wouldn'. They were worried bc my progesterone was rising, which means I was getting closer to ovulation and my eggs could have been overlymature (No way of that!)

This last time it was the 9th thru the 20th, so 11 days.
__________________


for God to bless us

Me: No problems known
DH: Perfect

Sept: IVF #1
Follistem 225
Menopur 75
ER 15 follicles
12 eggs
only 3 mature
2 fert with ICSI
NO embies to go to ET

Began birth control pills waiting for

October IVF
RE changed my medication dose
300 follistim
150 menopur
10-6 last birth control pill
10-9 u/s baseline test to begin stim
10-15 u/s showed 15 follies!
10-17 u/s showed 18 follies!!!!
10-19 u/s showed 19 follies!!!!
Biggest 1 was 23mm
ER 10-22
19 follies 19 eggs 7 mature ALL fert with ICSI!
ET 10-26 My dr does 4 day ET- transfered 3 embies 2 good quality 1 poor
BETA 11/6

POAS 6/1,2,3 VARY faint
POAS 6/4 DARK
PLEASE GOD BLESS US
Reply With Quote
  #9 (permalink)  
Old 11-01-2008, 10:09 AM
Waiting4thestork's Avatar
Waiting4thestork Waiting4thestork is offline
Member
 
Join Date: Sep 2008
Posts: 113
Quote:
Originally Posted by okitoki
Hi, LGB. This past cycle I also had a lot of immature eggs... Although my unmedicated cycles are pretty short-- 26 days with ovulation occurring during days 12-14.

I wondered actually for me if the trigger of 5K iu was too low and also whether they triggered me too soon. I've done some research on the internet about immature eggs, but haven't really found anything definitive. I am very interested in this topic, so please let me know if you make any discoveries...

With your thyroid cond have they tested you for auto immune? My moms side of the family this runs really deep, and they wanted to make sure I didnt have anything wrong with my thyroid before beginning IVF, my RE said it is a completly different ball game for those who have thyroid disorders.
__________________


for God to bless us

Me: No problems known
DH: Perfect

Sept: IVF #1
Follistem 225
Menopur 75
ER 15 follicles
12 eggs
only 3 mature
2 fert with ICSI
NO embies to go to ET

Began birth control pills waiting for

October IVF
RE changed my medication dose
300 follistim
150 menopur
10-6 last birth control pill
10-9 u/s baseline test to begin stim
10-15 u/s showed 15 follies!
10-17 u/s showed 18 follies!!!!
10-19 u/s showed 19 follies!!!!
Biggest 1 was 23mm
ER 10-22
19 follies 19 eggs 7 mature ALL fert with ICSI!
ET 10-26 My dr does 4 day ET- transfered 3 embies 2 good quality 1 poor
BETA 11/6

POAS 6/1,2,3 VARY faint
POAS 6/4 DARK
PLEASE GOD BLESS US
Reply With Quote
Reply


Currently Active Users Viewing This Thread: 1 (0 members and 1 guests)
 
Thread Tools Search this Thread
Search this Thread:

Advanced Search
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

vB code is On
Smilies are On
[IMG] code is Off
HTML code is Off
Trackbacks are Off
Pingbacks are Off
Refbacks are On


All times are GMT -7. The time now is 12:57 AM.


Powered by vBulletin Version 3.5.4
Copyright ©2000 - 2009, Jelsoft Enterprises Ltd.
Search Engine Friendly URLs by vBSEO 3.0.0 RC4