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Did Assisted Hatching Work For You??
I'm considering doing assisted hatching on my embryos during my next IVF cycle. My RE said it was probably a good idea since my previous 5dt of 2 blasts resulted in a BFN. However he said there is some literature floating around out there saying that AH is conter-productive in women under the age of 34, although no concrete studies agree. So I'm looking for both the good and bad stories...Did AH work for you??
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Me 32 - All tests seem fine DH 31 - Very Low Everything 2 furbabies TTC since June 2007March '08 to Aug '08 - Five IUI's, all IVF #1 Oct '08 w/ ICSI 9 eggs retrieved & 7 fertilized w/ ICSI 5 day transfer of 2 blasts, none to freeze IVF #2 Jan '09 w/ ICSI & AH 9 eggs retrieved & 7 fertilized w/ ICSI 3 day transfer of two 8-cell embryos, none to freeze ![]() IVF #3 April '09 w/ ICSI 19 Eggs Retrieved & 10 Fertilized w/ ICSI April 18 - 3 day transfer of two 8-cell embryos, none to freeze May 1 - Beta 13dp3dt 480!!!! May 5 - 1st u/s at 4 weeks, 6 days - 2 sacs ![]() May 27 - 3rd u/s at 8 wks, 2 strong heartbeats!! Aug 6 - u/s @ 18 weeks - Two GIRLS, each weighing 1/2 lb each!! Sept 22 - u/s @ 24 weeks - Girls doing great, both weighing just over 1 1/2 lbs each Oct 21 - u/s @ 28 weeks - baby A just shy of 3 lbs and baby B just over 3 lbs |
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Worked for us and we are doing IVF again in 2009 and will use ICSI for sure.
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Dre
Me: 34 (Issue: Endo)DH: 33 WONDERFUL Adopted DS 2005: 3 years old 3/5: 1st IVF: 5 day transfer of two blastocyst (1 grade 1, 1 grade 2) *TIME FOR BETA SCARE 3/14: 1st BETA 77 3/16: 2nd BETA 105 3/19: 3rd BETA 155 3/23: 4th BETA 631 4/2: 1st US = 6 weeks 3 days; 1 Heartbeat/w/baby in sac (Oh what a feeling!)8/10 ~ Hospitalized for Vasa Previa at 25 weeks for 3 months DD born 3 weeks early @37wks. www.vasaprevia.org/ FET 2 Embies on Ice ~ 1 grade 2, 1 grade 3 ET:7/24/08 BETA 7/31: POAS in AM, FAINT + 8/1: 1st Beta = 41 8/4: 2nd BETA =117 8/20: U/S @ 6 weeks 4 days (No HB) 8/25: U/S @ 7 weeks 2 days (No HB) 8/26: D&C ![]() Jan. 2009 ~IVF #2 + BETA Twins 3/4/09 D&C *Diagnosised with: Pregnancy related antiphospholipid antibody, Hasimoto's Disease 5/21/09 ~ + HPT TWINS AGAIN NATURALLY (w/5% chance of natural pregnancy) ![]() ![]() 2 Identical BOYS (shared placenta) Heprin 2x's a day (YUCK) EED: 1/21/10 |
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We did ISCI/AH and it worked for us so far!
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TTC since 07/2007 Erin: 39, one child (9 year old boy), no issues except age Jeff: 44, low morphology, low count, low motility, has epilepsy and takes meds IVF #1 in July '08--Lupron protocol Cycle canceled due to work/school obligations. IVF #1.5 in August/September '08--Antagonist protocol 9/26 3dt of 2 embryos 10/03, 10/04 HPT 10/05 HPT 10/07 Beta but low at 2910/09 Beta 65 10/11 Beta 224! 10/29 Ultrasound a beating heart! 12/4 Attempted CVS--it looks like a girl! 12/29 Amnio--results normal! Charlotte Elizabeth was born June 17, 2009! 6 lbs 3 oz, 18.5 inches. http://purplegrackle.blogspot.com/ |
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I am 32 and did AH on my 5th and 6th IVF cycle. I really believe that is why I was finally successful.
Good Luck!
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TTC since 8/04 (unexplained infertility) IUI#1 05/06 bfn IUI#2 07/06 bfn IUI#3 09/06 bfn IVF#1 11/06 bfn IVF#2 01/07 bfn IVF#3 03/07 bfp (M/C 7W 6 DAYS) IVF#4 07/07 bfn IVF#5 10/07 bfp (M/C 5 WEEKS) IVF#6 3 ET on 1/21 (3 embies trans) + HPT 1/29,1/30,& 1/31 BFP 2/01 beta 205 (spotting) 2/04 beta 480 (small amount of bleeding RED) 2/14 first U/S H/B 107 - 2/25 2nd U/S H/B 152 5/9 Level II ultrasound (Anatomy/Gender) GIRL! Due 10/10/08- DD was born 10/01/08 6lbs 13 oz 20.5 inches IVF#7 ER on 6/11 for baby #2 ET on 6/14 3 trans +hpt on 6/21,6/22,6/23 BFP beta on 6/25 440 beta 6/28 1116 Sweat Pea(s) twins are due 3/4 10/1 U/S Baby A Boy Baby B unknown 11/5 US Baby A still Boy and Baby B Girl
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We were TTC for six year and had four IVF cycles. We had Assisted Hatching done on our fourth and last cycle and got our BFP! I'm now 11 weeks. I say do it, do it, do it! ha ha. It worked for us and we had been given a 30% of having a pregnancy with my eggs.
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Kelli Me-37 (DOR) DH -42 (MF) Bella Cooper TTC - 7 years Sept. 2004 - IVF (BFN), Dec. 2004 - IVF (BFN) 2005-2007 - Break (TTC Naturally) 3rd IVF March 2008 - BFN, continuing acupuncture, DHEA & Royal Jelly. New RE IVF #4 - September (Antagonist Protocol) ER 9/19 Four eggs retrieved. 9/20 - All four fertilized and looking great! ET - 9/22. Two great embabies transferred with assisted hatching. Come on embabies snuggle in! Beta 10/1 - 39.5 , Beta 10/3 - 77.4 , Beta 10/6 - 208, Beta 10/13 - 2,278 1st Ultrasound 10/20 - one little bean and we saw the heartbeat!! 2nd Ultrasound 10/28 - heard the heartbeat and baby doing great! Graduated to the OB! Due Date June 12, 2009 Our little miracle...Devon Noble born June 15, 2009 - 10lbs, 1oz, 22" long.
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I asked my RE about assisted hatching and this is the reply they sent me.
AHA isn't needed with ICSI. WIth ICSI, the egg is stripped and a hole is made for the injection of the sperm accomplishing the same thing as AHA! I trust my RE but did anyone else know that with ICSI assisted hatching is already done? Alex
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Me:38 - mild endo DH:39 - low motility 2 Cocker Spaniels - Cody and KarmaTTC since 2006 3 IUI - all IVF #1 Oct.2007 m/c at 8 wks FET Oct. 2008- IVF #2 - Dec. 2008 11/ 4 - start BCP 11/23 -stop BCP 11/27 - stim meds - gonal F, menopur, cetrotide 12/10 - ER retrieved 15 eggs, 12 mature, 6 fertilized 12/13 - ET - 3 day - all 8 cell, 1 grade 1, 2 grade 2 12/23 - Beta #1 = 131, Beta #2 = 1,9991//6 - u/s 1 little Bean 1/13 u/s everything looks great hr -127 graduated to OB 1/27 1st OB appt. 2/17 NT Scan -- everything looked great EDD August 19th |
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I did read on the internet that ICSI acts as Assisted Hatching. But I read that after my consult w/ my RE, so the next time I talk to the office I'm going to ask.
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Me 32 - All tests seem fine DH 31 - Very Low Everything 2 furbabies TTC since June 2007March '08 to Aug '08 - Five IUI's, all IVF #1 Oct '08 w/ ICSI 9 eggs retrieved & 7 fertilized w/ ICSI 5 day transfer of 2 blasts, none to freeze IVF #2 Jan '09 w/ ICSI & AH 9 eggs retrieved & 7 fertilized w/ ICSI 3 day transfer of two 8-cell embryos, none to freeze ![]() IVF #3 April '09 w/ ICSI 19 Eggs Retrieved & 10 Fertilized w/ ICSI April 18 - 3 day transfer of two 8-cell embryos, none to freeze May 1 - Beta 13dp3dt 480!!!! May 5 - 1st u/s at 4 weeks, 6 days - 2 sacs ![]() May 27 - 3rd u/s at 8 wks, 2 strong heartbeats!! Aug 6 - u/s @ 18 weeks - Two GIRLS, each weighing 1/2 lb each!! Sept 22 - u/s @ 24 weeks - Girls doing great, both weighing just over 1 1/2 lbs each Oct 21 - u/s @ 28 weeks - baby A just shy of 3 lbs and baby B just over 3 lbs |
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I heard that too, but since we were down to three embryos post transfer I felt the $300 extra for AH was probably worth it. We wound up with just two embryos to transfer, so I'm glad we did the AH. We will never know if that made the difference between success and failure, but I'm pregnant with a singleton now, so I'm glad I spent the extra money.
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TTC since 07/2007 Erin: 39, one child (9 year old boy), no issues except age Jeff: 44, low morphology, low count, low motility, has epilepsy and takes meds IVF #1 in July '08--Lupron protocol Cycle canceled due to work/school obligations. IVF #1.5 in August/September '08--Antagonist protocol 9/26 3dt of 2 embryos 10/03, 10/04 HPT 10/05 HPT 10/07 Beta but low at 2910/09 Beta 65 10/11 Beta 224! 10/29 Ultrasound a beating heart! 12/4 Attempted CVS--it looks like a girl! 12/29 Amnio--results normal! Charlotte Elizabeth was born June 17, 2009! 6 lbs 3 oz, 18.5 inches. http://purplegrackle.blogspot.com/ |
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I did icsi with all 6 of my cycles but AH with the last 2. They must do something different because I was required to take doxycycline those 2 times. It also worked both times!
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TTC since 8/04 (unexplained infertility) IUI#1 05/06 bfn IUI#2 07/06 bfn IUI#3 09/06 bfn IVF#1 11/06 bfn IVF#2 01/07 bfn IVF#3 03/07 bfp (M/C 7W 6 DAYS) IVF#4 07/07 bfn IVF#5 10/07 bfp (M/C 5 WEEKS) IVF#6 3 ET on 1/21 (3 embies trans) + HPT 1/29,1/30,& 1/31 BFP 2/01 beta 205 (spotting) 2/04 beta 480 (small amount of bleeding RED) 2/14 first U/S H/B 107 - 2/25 2nd U/S H/B 152 5/9 Level II ultrasound (Anatomy/Gender) GIRL! Due 10/10/08- DD was born 10/01/08 6lbs 13 oz 20.5 inches IVF#7 ER on 6/11 for baby #2 ET on 6/14 3 trans +hpt on 6/21,6/22,6/23 BFP beta on 6/25 440 beta 6/28 1116 Sweat Pea(s) twins are due 3/4 10/1 U/S Baby A Boy Baby B unknown 11/5 US Baby A still Boy and Baby B Girl
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Quote:
Christy, how soon did you start the doxycycline? My office has not been too helpful in assisting me to have AH part of this cycle. I am not done pushing this subject but I am afraid it will be to late to have this done since I start stims thursday. Alex
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Me:38 - mild endo DH:39 - low motility 2 Cocker Spaniels - Cody and KarmaTTC since 2006 3 IUI - all IVF #1 Oct.2007 m/c at 8 wks FET Oct. 2008- IVF #2 - Dec. 2008 11/ 4 - start BCP 11/23 -stop BCP 11/27 - stim meds - gonal F, menopur, cetrotide 12/10 - ER retrieved 15 eggs, 12 mature, 6 fertilized 12/13 - ET - 3 day - all 8 cell, 1 grade 1, 2 grade 2 12/23 - Beta #1 = 131, Beta #2 = 1,9991//6 - u/s 1 little Bean 1/13 u/s everything looks great hr -127 graduated to OB 1/27 1st OB appt. 2/17 NT Scan -- everything looked great EDD August 19th |
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Alex, I think you still have plenty of time. My RE told me the final decision regarding AH wouldn't be made until after ER and once they were able to see the embryos.
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Me 32 - All tests seem fine DH 31 - Very Low Everything 2 furbabies TTC since June 2007March '08 to Aug '08 - Five IUI's, all IVF #1 Oct '08 w/ ICSI 9 eggs retrieved & 7 fertilized w/ ICSI 5 day transfer of 2 blasts, none to freeze IVF #2 Jan '09 w/ ICSI & AH 9 eggs retrieved & 7 fertilized w/ ICSI 3 day transfer of two 8-cell embryos, none to freeze ![]() IVF #3 April '09 w/ ICSI 19 Eggs Retrieved & 10 Fertilized w/ ICSI April 18 - 3 day transfer of two 8-cell embryos, none to freeze May 1 - Beta 13dp3dt 480!!!! May 5 - 1st u/s at 4 weeks, 6 days - 2 sacs ![]() May 27 - 3rd u/s at 8 wks, 2 strong heartbeats!! Aug 6 - u/s @ 18 weeks - Two GIRLS, each weighing 1/2 lb each!! Sept 22 - u/s @ 24 weeks - Girls doing great, both weighing just over 1 1/2 lbs each Oct 21 - u/s @ 28 weeks - baby A just shy of 3 lbs and baby B just over 3 lbs |
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AH with ICSI was the key to our success! So, if you have the means and your practice offers it I say you should definitely give it a try. Good Luck!
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Me - PCOS DH - MF 7/08 - 4th round of IVF (1 canceled cycle, 2 )3/08 Changed RE's for cycle #4 FET necessary due to OHSS... 7/19 - ![]() 1st Beta - 175 2nd Beta - 566 3rd Beta - 2544 7/25 - 1st U/S - One sac and yolk! ![]() 8/1 - for a heartbeat - 122 bpm Praise God!! I'm so thankful I want to just shout and dance all day!![]() 11/7 - Anatomy scan... "Let's hear it for the boys!"![]() ![]() |
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I started doxycycline and methylprednisolone after ER.
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TTC since 8/04 (unexplained infertility) IUI#1 05/06 bfn IUI#2 07/06 bfn IUI#3 09/06 bfn IVF#1 11/06 bfn IVF#2 01/07 bfn IVF#3 03/07 bfp (M/C 7W 6 DAYS) IVF#4 07/07 bfn IVF#5 10/07 bfp (M/C 5 WEEKS) IVF#6 3 ET on 1/21 (3 embies trans) + HPT 1/29,1/30,& 1/31 BFP 2/01 beta 205 (spotting) 2/04 beta 480 (small amount of bleeding RED) 2/14 first U/S H/B 107 - 2/25 2nd U/S H/B 152 5/9 Level II ultrasound (Anatomy/Gender) GIRL! Due 10/10/08- DD was born 10/01/08 6lbs 13 oz 20.5 inches IVF#7 ER on 6/11 for baby #2 ET on 6/14 3 trans +hpt on 6/21,6/22,6/23 BFP beta on 6/25 440 beta 6/28 1116 Sweat Pea(s) twins are due 3/4 10/1 U/S Baby A Boy Baby B unknown 11/5 US Baby A still Boy and Baby B Girl
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Hopefully my last question on assisted hatching.
My RE is having us speak with our clinic but they haven't called back so I haven't gotten to ask how much assisted hatching costs. We are very excited our clinic does it and our RE is now on board if we want to do it. From the research I have done it looks like anywhere from $250 to $500. We are out of pocket so it is a consideration for us. If I may ask, how much was it in your area of the US? Thank you guys for all your support in this. We really want to do AH and will borrow as much money as we need to to make that happen. Alex
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Me:38 - mild endo DH:39 - low motility 2 Cocker Spaniels - Cody and KarmaTTC since 2006 3 IUI - all IVF #1 Oct.2007 m/c at 8 wks FET Oct. 2008- IVF #2 - Dec. 2008 11/ 4 - start BCP 11/23 -stop BCP 11/27 - stim meds - gonal F, menopur, cetrotide 12/10 - ER retrieved 15 eggs, 12 mature, 6 fertilized 12/13 - ET - 3 day - all 8 cell, 1 grade 1, 2 grade 2 12/23 - Beta #1 = 131, Beta #2 = 1,9991//6 - u/s 1 little Bean 1/13 u/s everything looks great hr -127 graduated to OB 1/27 1st OB appt. 2/17 NT Scan -- everything looked great EDD August 19th |
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